Controlled trial of nomifensin (HOE 984) and viloxazine in the treatment of depression in the elderly.

Author: MoizeszowiczJ, SubiráS

Paper Details 
Original Abstract of the Article :
The new antidepressant nomifensin (Hoechst 36984), a drug which showed less cardiotoxicity than tricyclics, was compared in a single-blind comparative trial with viloxazine. Forty elderly depressed patients were treated during four weeks. Nomifensin, N=21, 75 mg/day; viloxazine, N=19, 150 mg/day). A...See full text at original site
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引用元:
https://doi.org/10.1002/j.1552-4604.1977.tb04589.x

データ提供:米国国立医学図書館(NLM)

Nomifensin and Viloxazine: A Comparative Oasis in the Desert of Depression

This research compares the efficacy of two antidepressants, nomifensin and viloxazine, in treating depression in older adults. It’s like exploring two oases in a vast desert, each offering potential relief from the scorching heat of depression. The authors conducted a single-blind comparative trial involving 40 elderly patients with depression, randomly assigned to receive either nomifensin or viloxazine for four weeks. The results showed statistically significant improvements in depression scores for both treatment groups, but nomifensin showed a more pronounced improvement from the second week onwards. This research offers valuable insights into the therapeutic landscape for depression in older adults.

The Desert of Depression: Seeking Relief

The study suggests that both nomifensin and viloxazine can be effective in treating depression in older adults, but nomifensin showed a faster onset of action. It’s like discovering two oases in a desert, one offering immediate relief from the harsh conditions while the other provides a more gradual and sustained source of respite.

Nomifensin and Viloxazine: Finding Hope in the Desert

This research provides hope for those struggling with depression in later life. It’s like finding a beacon of light in the vast desert, offering a path to relief and a chance for a brighter future.

Dr. Camel's Conclusion

This research underscores the importance of exploring different treatment options for depression in older adults. It’s like finding a new path in a vast desert, offering hope for a brighter future. The study suggests that both nomifensin and viloxazine can be effective, but nomifensin may offer a faster path to improvement.

Date :
  1. Date Completed 1977-03-15
  2. Date Revised 2019-08-23
Further Info :

Pubmed ID

319120

DOI: Digital Object Identifier

10.1002/j.1552-4604.1977.tb04589.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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