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Effects of short-term cannabidiol treatment on response to social stress in subjects at clinical high risk of developing psychosis.

Author: Appiah-KusiE, BhattacharyyaS, BossongM G, ColizziM, McGuireP, MondelliV, PetrosN, ValmaggiaL, WilsonR

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

CBD may normalize the neuroendocrine and anxiety responses to stress in clinical high risk for psychosis patients. In this study, CHR patients on CBD exhibited an intermediate cortisol reactivity compared to controls and placebo groups, suggesting a potential benefit. Further research is needed to investigate whether CBD can affect cortisol response and impact symptoms in CHR patients.
Paper Details　
Original Abstract of the Article :
RATIONALE: Stress is a risk factor for psychosis and treatments which mitigate its harmful effects are needed. Cannabidiol (CBD) has antipsychotic and anxiolytic effects. OBJECTIVES: We investigated whether CBD would normalise the neuroendocrine and anxiety responses to stress in clinical high risk...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113209/

データ提供：米国国立医学図書館（NLM）

Cannabidiol: A Potential Oasis in the Desert of Psychosis

Navigating the [desert of psychosis] is fraught with uncertainty and challenges. This study explores the potential of [cannabidiol (CBD)] to [mitigate the effects of stress] in individuals at [clinical high risk of developing psychosis (CHR)]. The researchers investigated the [neuroendocrine and anxiety responses to stress] in CHR patients who received [CBD] or a [placebo] for one week. Their findings provide insights into the potential benefits of [CBD] in [managing stress and anxiety] in this vulnerable population.

Exploring the Oasis of Cannabidiol: A New Approach to Psychosis

The study found that [CBD] had a [significant effect on cortisol reactivity] in CHR patients, demonstrating a [reduced cortisol response to stress]. This suggests that [CBD] may have the ability to [modulate the stress response] in these individuals. While further research is necessary, these findings offer promising evidence for the potential of [CBD] to [alleviate stress-related symptoms] in CHR patients.

A Camel's Perspective on Cannabidiol: A Glimpse of Hope

This study reminds us that the desert of [psychosis] is not entirely barren. The potential of [CBD] to [alleviate stress and anxiety] in individuals at risk of developing psychosis is a beacon of hope. This research suggests that [CBD] may offer a new path for managing stress and preventing the development of psychosis. The potential of [CBD] to improve the lives of individuals at risk of psychosis is a testament to the ongoing efforts to find solutions in the challenging landscape of [mental health].

Dr. Camel's Conclusion

This research provides promising evidence for the potential of CBD to alleviate stress and anxiety in individuals at clinical high risk of developing psychosis. While further research is needed to confirm these findings, this study offers a glimmer of hope for those navigating the desert of psychosis. The potential of CBD to help individuals manage stress and prevent the development of psychosis is a testament to the ongoing pursuit of new treatments and therapies in mental health.

Date :
  1. Date Completed 2020-09-14
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

31915861

DOI: Digital Object Identifier

PMC7113209

Related Literature

Article Analysis
・Effects of cannabidiol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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