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Effect of Midazolam in Addition to Propofol and Opiate Sedation on the Quality of Recovery After Colonoscopy: A Randomized Clinical Trial.

Author: BoggettStuart, BowyerAndrea, GurunathanUsha, HarchJennifer, HillCindy, RahmanTony, RoyseColin, SriramSweta, VandeleurAnn, WilliamsZelda

Clinical Trial, Phase IVPost-marketing surveillance. Monitors long-term safety/efficacy after approval.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Midazolam, as an adjunct to propofol and opiate sedation for elective colonoscopy, did not show any significant differences in recovery in the cognitive domain, overall quality of recovery, or emergence and hospital discharge times.
Paper Details　
Original Abstract of the Article :
BACKGROUND: There is a concern that midazolam, when used as a component of sedation for colonoscopy, may impair cognition and prolong recovery. We aimed to identify whether midazolam produced short- and longer-term effects on multiple dimensions of recovery including cognition. METHODS: A 2-center ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/31922999

データ提供：米国国立医学図書館（NLM）

Midazolam's Role in Colonoscopy Sedation: A Quest for Optimal Recovery

The world of gastroenterology is always seeking ways to improve patient comfort and ensure a smooth recovery. This research focuses on the role of midazolam, a common sedative used during colonoscopy procedures. The study aimed to understand whether midazolam, when combined with propofol and opiate sedation, impacted cognitive function and recovery time. The researchers designed a double-blinded, placebo-controlled study, akin to a carefully crafted experiment in a controlled desert environment, allowing for a clear comparison of the effects of midazolam and placebo.

Midazolam: A Neutral Player in Colonoscopy Recovery

The study found no significant difference in cognitive recovery, overall quality of recovery, or emergence and hospital discharge times between patients who received midazolam and those who received a placebo. This suggests that midazolam, when used as an adjunct to propofol and opiate sedation, does not negatively impact recovery after colonoscopy. The results provide valuable information for physicians to make informed decisions about sedation protocols.

Navigating the Desert of Colonoscopy Recovery

This research, like a well-mapped path through the desert of colonoscopy recovery, provides valuable insights into the impact of midazolam on patient outcomes. The findings suggest that, while midazolam may offer benefits in some cases, it does not appear to hinder recovery. This knowledge empowers physicians to make informed decisions about sedation protocols, ultimately leading to better patient experiences.

Dr.Camel's Conclusion

This study, like a clear spring in the desert of colonoscopy recovery, sheds light on the role of midazolam in sedation. The findings indicate that midazolam, when used in conjunction with other sedatives, does not appear to compromise patient recovery. It offers valuable information for physicians to make informed decisions about sedation protocols, ultimately leading to more comfortable and efficient procedures.

Date :
  1. Date Completed 2020-11-16
  2. Date Revised 2021-01-26
Further Info :

Pubmed ID

31922999

DOI: Digital Object Identifier

00000539-202009000-00016

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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