Synergistic Effects of the 308-nm Excimer Light and Topical Calcipotriol for the Treatment of Chronic Hand Eczema: A Randomized Controlled Study.

Author: ChunhakhamPradtana, JuntongjinPremjit

Paper Details 
Original Abstract of the Article :
BACKGROUND: Though topical corticosteroid is a standard treatment for chronic hand eczema (CHE), it can cause many adverse effects. Topical calcipotriol and monochromatic 308-nm excimer light (MEL) are new alternative therapies for several dermatoses, including CHE. OBJECTIVE: This study aims to co...See full text at original site
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引用元:
https://doi.org/10.1159/000505539

データ提供:米国国立医学図書館(NLM)

Treating Hand Eczema: The Power of Light and Calcipotriol

Chronic hand eczema (CHE) is a persistent and often bothersome skin condition that can significantly impact a person's quality of life. This study explores the efficacy of a combination therapy for CHE, utilizing monochromatic 308-nm excimer light (MEL) and topical calcipotriol. The research team aimed to compare the effectiveness of this combination therapy with topical calcipotriol alone, seeking to provide a more effective and potentially less side-effect-prone treatment for CHE.

A Shining Solution: MEL and Calcipotriol Together

This research, like a desert traveler discovering a hidden oasis, sheds light on the potential of combining MEL and topical calcipotriol for treating CHE. The study found that this combination therapy significantly reduced the severity of CHE, compared to topical calcipotriol alone. The combination therapy led to a more rapid and sustained reduction in eczema severity, as measured by the Hand Eczema Severity Index (HECSI), indicating a potential advantage over monotherapy. The findings suggest that this combination therapy could provide a more effective and potentially less side-effect-prone treatment for CHE.

A Brighter Future for CHE: Combination Therapy and Hope

This research, like a sunbeam piercing through the desert sands, offers hope for individuals struggling with CHE. The study demonstrated that combining MEL and topical calcipotriol could significantly improve the condition's severity, potentially reducing the need for traditional corticosteroid treatments and their associated side effects. This discovery represents a promising step forward in managing CHE and improving the lives of those affected by it.

Dr.Camel's Conclusion

The desert of skin conditions can be challenging to navigate, and CHE can be a particularly stubborn traveler. This study, like a resourceful explorer, reveals the potential of combining MEL and topical calcipotriol to combat CHE, potentially offering a more effective and less side-effect-prone treatment. This discovery could illuminate a brighter path for individuals struggling with CHE, providing them with greater relief and improved quality of life.

Date :
  1. Date Completed 2021-10-19
  2. Date Revised 2021-10-19
Further Info :

Pubmed ID

31982887

DOI: Digital Object Identifier

10.1159/000505539

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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