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Mechanisms of Action of Cassiae Semen for Weight Management: A Computational Molecular Docking Study of Serotonin Receptor 5-HT2C.
Author: HungAndrew, LenonGeorge Binh, YangAngela Wei Hong, YuenHeidi
Original Abstract of the Article :
Overweight and obesity is a growing global health concern. Current management of obesity includes lifestyle intervention, bariatric surgery and medication. The serotonin receptor, 5-HT2C, is known to mediate satiety, appetite and consumption behaviour. Lorcaserin, an appetite control drug, has demon...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072867/
データ提供:米国国立医学図書館(NLM)
Cassiae Semen: A Traditional Chinese Medicine with Potential for Weight Management
Obesity, a global health concern, is like a desert that can be difficult to navigate. This computational molecular docking study investigates the potential use of Cassiae semen (CS), a traditional Chinese medicine, for weight management. The researchers focused on the serotonin receptor 5-HT2C, a key player in appetite regulation. They explored the potential binding mechanisms of CS compounds to this receptor to understand how they might influence appetite control.
Unlocking the Potential of Traditional Remedies: CS Compounds and 5-HT2C
The study found that two specific CS compounds, obtusifoliol and cassiaside B2, may act as potent agonists for the 5-HT2C receptor, potentially mimicking the appetite-suppressing effects of lorcaserin, a currently used appetite control medication. These findings suggest that CS could offer a natural approach to weight management.
A New Oasis for Weight Management: CS Compounds and Appetite Control
This study opens the door to exploring the potential of traditional Chinese medicine, like CS, in addressing modern health challenges like obesity. Further research is needed to confirm the safety and efficacy of CS compounds in humans. However, this study offers a promising glimpse into the potential of natural remedies for weight management.
Dr. Camel's Conclusion
This computational molecular docking study explores the intriguing potential of Cassiae semen as a natural approach to weight management by targeting the serotonin receptor 5-HT2C. It's a reminder that ancient wisdom can provide valuable insights into modern health challenges, and that further research is essential to harness the full potential of natural remedies.
Date :
- Date Completed 2020-11-20
- Date Revised 2020-11-20
Further Info :
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