Isolated nail lichen planus: An expert consensus on treatment of the classical form.

Author: BaranRobert, DanielC Ralph, Di ChiacchioNilton, GoettmannSophie, GroverChander, HanekeEckart, IorizzoMatilde, LipnerShari R, PiracciniBianca Maria, RichPhoebe, RichertBertrand, RigopoulosDimitris, RubinAdam I, StaraceMichela, TostiAntonella, ZaiacMartin

Paper Details 
Original Abstract of the Article :
Lichen planus is a benign inflammatory disorder of unknown etiology that may affect the skin, mucosae, scalp, and nails. When the nails are affected, it may lead to permanent destruction with severe functional and psychosocial consequences. Therefore, prompt diagnosis and early treatment are essenti...See full text at original site
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引用元:
https://doi.org/10.1016/j.jaad.2020.02.056

データ提供:米国国立医学図書館(NLM)

Addressing the Challenge of Nail Lichen Planus: A Consensus on Treatment

Lichen planus, a condition that can feel like a persistent desert wind, affects the skin, mucous membranes, scalp, and nails, causing discomfort and potential for permanent damage. This study focuses on the impact of lichen planus on nails, a particularly challenging area, as it can lead to significant functional and psychosocial consequences. This research, much like a group of desert nomads sharing their expertise, brings together a panel of experts to develop consensus-based recommendations for managing this condition.

The experts, like seasoned travelers navigating the desert, recognize the importance of early diagnosis and treatment to prevent further complications. However, the path to effective treatment is not straightforward. Current literature on nail lichen planus is limited, and there are no established guidelines, similar to navigating an uncharted desert. This study, therefore, serves as a valuable guide for clinicians, providing practical recommendations specifically for the classical form of nail lichen planus, when it affects primarily the nails.

Topical Treatments: A Limited Oasis

The experts caution that topical treatments, while seemingly straightforward, offer limited short-term benefits and may even lead to long-term side effects. This is similar to finding a temporary oasis that might not sustain a traveler on a long journey. Instead, they recommend intralesional and intramuscular triamcinolone acetonide as first-line therapies, like discovering a more permanent and reliable oasis.

Oral Retinoids and Immunosuppressive Agents: Alternate Paths in the Desert

The study also explores alternative treatment options, similar to finding different paths through the desert. Oral retinoids are suggested as second-line choices, and immunosuppressive agents, like finding a hidden oasis, might also be considered. However, the experts emphasize the need for careful consideration and close monitoring when using these therapies, recognizing that each approach has its own set of challenges and risks, like the potential for unexpected hazards in the desert.

Dr.Camel's Conclusion

The challenge of treating nail lichen planus is like navigating a vast and often unforgiving desert. This study, like a group of experienced desert guides, offers valuable insights and practical recommendations, guiding clinicians toward more effective treatment strategies for this challenging condition. However, the journey is far from over, and further research is needed to identify even more reliable and sustainable oases, ultimately ensuring a better outcome for those affected by this condition.

Date :
  1. Date Completed 2021-04-23
  2. Date Revised 2021-04-23
Further Info :

Pubmed ID

32112995

DOI: Digital Object Identifier

10.1016/j.jaad.2020.02.056

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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