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A case report of immune-mediated arthritis in a patient with cutaneous melanoma receiving checkpoint inhibition therapy.
Author: AnastasopoulouAmalia, BenopoulouOlga, DiamantopoulosPanagiotis, GogasHelen, LaskariKaterina, PapaxoinisGeorge
Original Abstract of the Article :
Immune checkpoint inhibitors (ICIs) represent an important advance in the treatment of melanoma. ICIs may induce autoimmune phenomena caused by concurrent activation of the immune system against normal cells. During the last years, cases of musculoskeletal side effects, especially immune-mediated ar...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478575/
データ提供:米国国立医学図書館(NLM)
Immune Checkpoint Inhibitors and Arthritis: A Tale of Two Camels
This study explores a rare case of immune-mediated arthritis (IA) in a patient with melanoma receiving immune checkpoint inhibitor (ICI) therapy. It's like watching two camels, one healthy and one sick, interacting in the desert – a fascinating and unexpected encounter.
The study highlights the potential for ICIs to trigger autoimmune reactions, such as IA. This is a rare but important side effect that healthcare professionals should be aware of. It's like the healthy camel inadvertently spreading a disease to the sick camel – the immune system can sometimes turn against itself.
Navigating the Immune System
This research raises awareness about the potential for ICIs to induce autoimmune reactions. It's like navigating a complex desert ecosystem – we need to be mindful of the potential interactions between different elements.
A Balancing Act
This case report emphasizes the importance of careful monitoring for autoimmune side effects in patients receiving ICI therapy. It's like observing a delicate balance in the desert – we need to be vigilant about the impact of our interventions.
Dr.Camel's Conclusion
The development of IA in a patient receiving ICI therapy highlights the complex nature of the immune system. It's like watching two camels interact in the desert – their relationship is delicate, and unforeseen events can disrupt the balance.
Date :
- Date Completed 2020-03-16
- Date Revised 2023-12-13
Further Info :
Related Literature
English
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