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Effect of mirabegron on cognitive function in elderly patients with overactive bladder: MoCA results from a phase 4 randomized, placebo-controlled study (PILLAR).
Author: CampbellNoll L, ElsoudaDina, GrieblingTomas L, HerschornSender, MangelJeffrey, SchermerCarol R, StaskinDavid
Original Abstract of the Article :
Label="BACKGROUND">Antimuscarinics are often used for treatment of overactive bladder (OAB), but exposure to medications such as antimuscarinics that have anticholinergic properties has been linked to adverse cognitive effects. A phase 4 placebo-controlled study (PILLAR; NCT02216214) described the e...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079371/
データ提供:米国国立医学図書館(NLM)
Mirabegron's Impact on Cognitive Function in Elderly Patients
Our brains are like delicate sandcastles, easily eroded by time and external factors. Medications, especially those with anticholinergic properties, can sometimes have unintended consequences on our cognitive function. This study investigated the effects of mirabegron, a medication used to treat overactive bladder, on the cognitive abilities of elderly patients.
Mirabegron and Cognitive Function: A Detailed Examination
The research involved a group of elderly patients with overactive bladder who were randomly assigned to receive either mirabegron or a placebo. Researchers used a standardized cognitive test, the Montreal Cognitive Assessment (MoCA), to assess any changes in cognitive function. The results revealed no significant difference in cognitive function between the mirabegron and placebo groups.
Navigating the Desert of Cognitive Health
This research provides reassurance that mirabegron, at least in the context of this study, does not appear to negatively impact cognitive function in elderly patients with overactive bladder. However, it's important to remember that everyone is different, and individual responses to medications can vary. It's always best to consult with a healthcare professional to discuss any concerns or potential side effects of medications.
Dr.Camel's Conclusion
This study suggests that mirabegron may be a safe and effective treatment option for overactive bladder in elderly patients, without compromising their cognitive health. It's like finding a hidden oasis in the vast desert of cognitive function – a place where both bladder control and mental clarity can flourish. However, further research is needed to confirm these findings and explore the long-term effects of mirabegron on cognitive function.
Date :
- Date Completed 2020-11-23
- Date Revised 2020-11-23
Further Info :
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