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Nanovesicular Photodynamic Clinical Treatment of Resistant Plantar Warts.

Author: AbdelfadeelDoaa, FadelMaha, KassabKawser, NasrMaha, SamyNevien, YassinGhada

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study investigated the efficiency of a nano-vesicular system (transfersomes) as a topical drug delivery system for the photosensitizer methylene blue (MB) in photodynamic therapy (PDT) for the treatment of plantar warts (PW). Transfersomal MB gel was found to be more effective than free MB gel, achieving a higher complete healing percentage at a lower number of treatment sessions.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Photodynamic therapy which involves the use of photosensitizer molecule activated by a light source was proven very promising for the treatment of dermatological diseases, especially the resistant ones such as recalcitrant Plantar Warts (PW). OBJECTIVE: However, its efficacy is hindered...See full text at original site
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引用元：
https://doi.org/10.2174/1567201817666200324142221

データ提供：米国国立医学図書館（NLM）

Nanovesicular Photodynamic Therapy for Resistant Plantar Warts

The field of [plantar wart treatment] is continually seeking safe and effective therapies, particularly for [resistant plantar warts (PW)]. This study explores the use of [nanovesicular photodynamic therapy (PDT)] for treating resistant PW, focusing on the potential benefits of using a [transfersomal delivery system] for the photosensitizer [methylene blue (MB)]. The researchers aimed to enhance the effectiveness of PDT by improving the delivery of MB to the target area.

Nanovesicular Photodynamic Therapy: A Promising Approach for Resistant Plantar Warts

The study found that MB transfersomal gel was more effective in achieving complete healing of PW lesions compared to free MB gel. The transfersomal delivery system significantly improved the effectiveness of PDT, leading to a higher healing rate and requiring fewer treatment sessions. Furthermore, the treatment was well-tolerated by patients, with no reports of pain or inflammation, and no recurrence of lesions during the follow-up period.

Plantar Warts: Seeking Effective Treatment Options

If you are struggling with resistant PW, talk to your dermatologist about available treatment options, including nanovesicular PDT. They can assess your individual case and recommend the most appropriate approach for managing your condition.

Dr. Camel’s Conclusion

This study provides compelling evidence for the effectiveness of nanovesicular PDT in treating resistant PW. The authors’ findings suggest that this innovative approach can significantly improve treatment outcomes while maintaining a high level of safety. The study is a valuable contribution to the field of dermatology, offering a new and promising option for managing this persistent condition. Remember, consulting with a dermatologist is essential for addressing any skin concerns and receiving personalized treatment recommendations.

Date :
  1. Date Completed 2021-06-04
  2. Date Revised 2021-06-04
Further Info :

Pubmed ID

32208117

DOI: Digital Object Identifier

10.2174/1567201817666200324142221

Related Literature

Article Analysis
・Effective treatment of warts
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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