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Association of Presalvage Radiotherapy PSA Levels After Prostatectomy With Outcomes of Long-term Antiandrogen Therapy in Men With Prostate Cancer.

Author: DenRobert B, DessRobert T, DignamJames J, EfstathiouJason A, FengFelix Y, GharzaiLaila A, HallWilliam A, JacksonWilliam C, JairathNeil K, JaworskiElizabeth M, KishanAmar U, LeeWilliam Robert, MahalBrandon A, MehraRohit, MichalskiJeff M, MorganTodd M, NguyenPaul L, PisanskyThomas M, ReichertZachary R, RosenthalSeth A, SandlerHoward M, SartorOliver, SchaefferEdward M, SchipperMatthew J, ShipleyWilliam U, SprattDaniel E, StishBradley J, SunYilun, WallingtonDavid G, ZietmanAnthony L, ZumstegZachery S

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

The NRG/RTOG 9601 study showed that adding long-term antiandrogen therapy to salvage radiotherapy (SRT) in men with recurrent prostate cancer was associated with overall survival (OS). This study seeks to identify predictive biomarkers for benefit from treatment.
Paper Details　
Original Abstract of the Article :
In men with recurrent prostate cancer, addition of long-term antiandrogen therapy to salvage radiotherapy (SRT) was associated with overall survival (OS) in the NRG/RTOG 9601 study. However, hormone therapy has associated morbidity, and there are no validated predictive biomarkers to identify which ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189892/

データ提供：米国国立医学図書館（NLM）

Navigating the Sands of Prostate Cancer Treatment

[Prostate cancer] is a common cancer among men, and while surgery and radiation therapy are effective treatment options, some patients may experience recurrence. This study explores the role of long-term antiandrogen therapy after salvage radiotherapy (SRT) for men with recurrent prostate cancer. Think of antiandrogen therapy as a camel caravan equipped with special tools to combat the disease, while SRT acts as a guide leading them across the harsh landscape of cancer.

Identifying the Right Path

Researchers analyzed data from a study that examined the use of antiandrogen therapy in addition to SRT for men with recurrent prostate cancer. They sought to determine if certain factors could predict which patients benefited most from this treatment. This exploration is like a camel caravan searching for the best route through a complex and challenging desert, seeking to optimize their journey.

Tailoring Treatment for Better Outcomes

This research highlights the need for personalized treatment strategies for men with prostate cancer. By identifying the factors that predict the effectiveness of antiandrogen therapy, clinicians can make more informed decisions about treatment options. It's like a camel caravan adapting their strategy based on the terrain, ensuring a more successful and efficient journey.

Dr. Camel's Conclusion

This study underscores the importance of personalized medicine in the treatment of prostate cancer. It's like a camel caravan utilizing a diverse set of tools and strategies to navigate the ever-changing desert landscape. This research could lead to more effective and tailored treatment approaches, improving outcomes and quality of life for men with prostate cancer.
Date :
  1. Date Completed 2021-01-04
  2. Date Revised 2023-03-21
Further Info :

Pubmed ID

32215583

DOI: Digital Object Identifier

PMC7189892

Related Literature

Article Analysis
・Effective treatment of prostate cancer
SNS
PICO Info
in preparation
Languages

English

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