Paper Details

  1. Home
  2. Paper Details

Adverse effects of cannabidiol: a systematic review and meta-analysis of randomized clinical trials.

Author: ChesneyEdward, EnglundAmir, FreemanTom P, GreenAlastair, McGuirePhilip, OliverDominic, SoviSimina, WilsonJack

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review and meta-analysis of the adverse effects of cannabidiol (CBD) across all medical indications found that CBD is generally well-tolerated with few serious adverse effects, however, interactions with other medications should be monitored carefully.
Paper Details　
Original Abstract of the Article :
Cannabidiol (CBD) is being investigated as a treatment for several medical disorders but there is uncertainty about its safety. We conducted the first systematic review and meta-analysis of the adverse effects of CBD across all medical indications. Double-blind randomized placebo-controlled clinical...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608221/

データ提供：米国国立医学図書館（NLM）

A Look at the Safety of Cannabidiol (CBD)

The world of medicine is filled with exciting discoveries, but it's crucial to approach new treatments with a discerning eye. This study investigates the safety of cannabidiol (CBD), a compound derived from cannabis, which is gaining popularity as a potential treatment for various medical conditions. Like a camel cautiously crossing a desert, researchers meticulously reviewed clinical trial data to assess the potential adverse effects of CBD.

CBD and Adverse Effects

The meta-analysis revealed that CBD may be associated with an increased risk of certain adverse events, particularly when used in combination with other medications. Think of it like combining different types of sand in the desert, some of which may not mix well. The study found a higher incidence of withdrawal due to adverse events, including issues related to liver function and pneumonia, primarily in studies involving children with epilepsy. However, outside of this specific population, the most common side effect associated with CBD was diarrhea.

Navigating CBD Use

The findings of this study are important for both patients and healthcare professionals. Like a camel navigating the desert, we must be mindful of the potential risks and benefits associated with CBD use. Further research is needed to fully understand the safety profile of CBD, particularly in different patient populations and when used in combination with other medications. The desert of medical knowledge is vast and ever-changing, and we must continue to explore it to ensure the safety and well-being of our patients.

Dr.Camel's Conclusion

The discovery of CBD's potential therapeutic benefits is exciting, but it's crucial to proceed with caution, like a camel traversing a new and unfamiliar terrain. This study highlights the need for ongoing research and careful monitoring of CBD use to fully understand its safety profile. It reminds us that the journey of medical discovery is an ongoing one, and we must continue to navigate it with knowledge, prudence, and a commitment to patient safety.
Date :
  1. Date Completed 2021-06-23
  2. Date Revised 2021-06-23
Further Info :

Pubmed ID

32268347

DOI: Digital Object Identifier

PMC7608221

Related Literature

Article Analysis
・Effects of cannabidiol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.