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Efficacy and Safety of Intralesional Triamcinolone Versus Combination of Triamcinolone with 5-Fluorouracil in the Treatment of Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis.

Author: FuZhong-Hua, GuoGuang-Hua, JiangZheng-Ying, LiaoXin-Cheng, LiuMing-Zhuo, MinDing-Hong, YuXiao-Ting

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This review examined the efficacy and safety of intralesional triamcinolone acetonide (TAC) and combination therapy with 5-fluorouracil (5-FU) for treating keloids and hypertrophic scars, highlighting the need for more research on these treatments.
Paper Details　
Original Abstract of the Article :
Although keloids and hypertrophic scars are common benign hyperproliferative growths of dermal fibroblasts, the clinical problems including physical and psychological problems are significant and impairing, with few proven treatments. Intralesional triamcinolone acetonide (TAC) and combination of TA...See full text at original site
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引用元：
https://doi.org/10.1007/s00266-020-01721-2

データ提供：米国国立医学図書館（NLM）

Efficacy and Safety of Triamcinolone Versus Triamcinolone with 5-Fluorouracil in Keloids and Hypertrophic Scars

Keloids and hypertrophic scars, those pesky reminders of past injuries, can be a real nuisance! They are common benign growths that can cause both physical and psychological discomfort. This study, like a skilled surgeon, explores the effectiveness and safety of two widely used treatments for keloids and hypertrophic scars: intralesional triamcinolone acetonide (TAC) and a combination of TAC with 5-fluorouracil (5-FU).

A Clearer Picture of Treatment Effectiveness

The study found that both TAC and the combination of TAC with 5-FU are frequently used for keloids and hypertrophic scars, but their efficacy and safety are still debated. The researchers conducted a comprehensive review and meta-analysis, which is like a treasure hunt, to unearth the most reliable evidence.

Navigating the Path to Healing

The results of this study can guide healthcare professionals in choosing the most appropriate treatment for their patients. It also highlights the need for further research to better understand the long-term effects and potential risks of these treatments.

Dr.Camel's Conclusion

Just as a camel can endure long journeys across harsh landscapes, patients with keloids and hypertrophic scars may face a long road to recovery. This study helps us understand the nuances of treatment options, allowing us to find the best path to healing.

Date :
  1. Date Completed 2021-01-06
  2. Date Revised 2022-05-31
Further Info :

Pubmed ID

32342167

DOI: Digital Object Identifier

10.1007/s00266-020-01721-2

Related Literature

Article Analysis
・Effective treatment of scars
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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