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What factors modify the effect of monthly bolus dose vitamin D supplementation on 25-hydroxyvitamin D concentrations?

Author: BerosAngela, CamargoCarlos A, KhawKay-Tee, LawesCarlene M M, ReidIan R, ScraggRobert, SluyterJohn D, ToopLes, WaayerDebbie, WuZhenqiang

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study found that the effectiveness of vitamin D supplements in raising blood levels of vitamin D (25(OH)D) was influenced by several factors. People with lower baseline vitamin D levels, higher body mass index (BMI), and less sun exposure saw less of an increase in their vitamin D levels after taking supplements. Women, older adults, and those who frequently drank alcohol, were taking vitamin D medication, or had asthma/COPD experienced a greater increase in vitamin D levels. Ethnicity, tobacco smoking, and vigorous physical activity did not seem to affect the response to vitamin D supplements.
Paper Details　
Original Abstract of the Article :
The increasing use of vitamin D supplements has stimulated interest in identifying factors that may modify the effect of supplementation on circulating 25-hydroxyvitamin D (25(OH)D) concentrations. Such information is of potential interest to researchers, clinicians and patients when deciding on bol...See full text at original site
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引用元：
https://doi.org/10.1016/j.jsbmb.2020.105687

データ提供：米国国立医学図書館（NLM）

Vitamin D Supplementation: A Sunny Side Effect

Vitamin D, often called the sunshine vitamin, plays a vital role in maintaining bone health and overall well-being. But sometimes, our bodies need a little extra sunshine, especially in the cold desert months. This research investigates the factors that affect how well our bodies absorb and utilize vitamin D supplements.

The researchers conducted a large study involving thousands of adults and found that a few factors can influence the effectiveness of vitamin D supplements. These factors included baseline vitamin D levels, body mass index, sun exposure, gender, age, and even certain health conditions like asthma or COPD.

A Personalized Approach to Vitamin D

This research highlights the importance of a personalized approach to vitamin D supplementation. It suggests that individuals with lower baseline vitamin D levels, higher body mass indices, and limited sun exposure may require higher doses or more frequent supplementation to achieve optimal levels. It's like understanding the different water needs of desert plants: some require more water than others to thrive.

A Reminder to Consult a Doctor

It's always best to consult with a healthcare professional before starting any new supplements, including vitamin D. They can help determine the appropriate dosage and ensure you're getting the right amount of sunshine to support your health.

Dr.Camel's Conclusion

This research emphasizes the individuality of our bodies' vitamin D needs. Like desert plants, we all need sunshine to thrive, but the amount we require can vary. Consulting with a doctor can help us find the right dose and ensure that we're getting enough sunshine to stay healthy.

Date :
  1. Date Completed 2020-11-04
  2. Date Revised 2020-11-04
Further Info :

Pubmed ID

32360596

DOI: Digital Object Identifier

10.1016/j.jsbmb.2020.105687

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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