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Pharmacological treatment of psoriatic arthritis: a systematic literature research for the 2019 update of the EULAR recommendations for the management of psoriatic arthritis.

Author: BaraliakosXenofon, DougadosMaxime, FalzonLouise, GossecLaure, KerschbaumerAndreas, McInnesIain, PrimdahlJette, SmolenJosef S, de WitMaarten, van der HeijdeDésirée

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Numerous disease-modifying antirheumatic drugs (DMARDs) have demonstrated efficacy in treating psoriatic arthritis (PsA), with varying effectiveness across manifestations. Safety considerations, including the risk of venous thromboembolic events with Janus kinase inhibitors, are crucial.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To perform an update of a review of the efficacy and safety of disease-modifying antirheumatic drugs (DMARDs) in psoriatic arthritis (PsA). METHODS: This is a systematic literature research of 2015-2018 publications on all DMARDs in patients with PsA, searching Medline, Embase and the Co...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1136/annrheumdis-2020-217163

データ提供：米国国立医学図書館（NLM）

Navigating the Landscape of Pharmacological Treatment for Psoriatic Arthritis

Psoriatic arthritis, a chronic inflammatory disease affecting both the skin and joints, can be a difficult journey for patients seeking relief. This systematic literature research, like a comprehensive desert expedition, explored the efficacy and safety of various disease-modifying antirheumatic drugs (DMARDs) in managing psoriatic arthritis.

Exploring the Efficacy and Safety of DMARDs in Psoriatic Arthritis

The researchers meticulously reviewed publications from 2015 to 2018, evaluating the efficacy and safety of different DMARDs, including TNF inhibitors, IL-17A inhibitors, IL-23-p19 inhibitors, and others. Their findings revealed a wide range of treatment options, each with its own unique benefits and risks. This comprehensive analysis, like a desert map guiding explorers through diverse terrains, offers valuable insights for healthcare providers to make informed decisions about treatment strategies.

Guiding Treatment Decisions for Psoriatic Arthritis

This review underscores the importance of considering the specific needs and characteristics of each patient when choosing a DMARD for psoriatic arthritis. The researchers emphasize the need to weigh the potential benefits of each drug against its potential risks, ensuring that patients receive the most appropriate care for their individual needs. This thoughtful approach, like carefully choosing the right path through a vast desert, helps to optimize treatment outcomes and minimize potential side effects.

Dr.Camel's Conclusion

The landscape of psoriatic arthritis treatment options is vast and diverse, like a sprawling desert with multiple paths to explore. This review offers valuable insights into the efficacy and safety of different DMARDs, helping healthcare providers to navigate this complex terrain and provide personalized care for patients living with this challenging condition.

Date :
  1. Date Completed 2020-07-07
  2. Date Revised 2020-07-07
Further Info :

Pubmed ID

32381564

DOI: Digital Object Identifier

10.1136/annrheumdis-2020-217163

Related Literature

Article Analysis
・Effective treatment of psoriatic arthritis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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