Antinociceptive effects of ceftriaxone in formalin-induced nociception.

Author: Baeza-FloresGuadalupe Del Carmen, Guzmán-PriegoCrystell G, Reyes-PérezValeria, Rodríguez-PalmaErick J, Torres-LópezJorge E

Paper Details 
Original Abstract of the Article :
Ceftriaxone (CFX) is a β-lactam antibiotic with analgesic properties. However, its role in the formalin-induced nociception remains unknown. The purpose of this study was to investigate the antinociceptive effect of CFX in the 1% formalin test in rats. Formalin induced a typical nociceptive response...See full text at original site
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引用元:
https://doi.org/10.1002/ddr.21680

データ提供:米国国立医学図書館(NLM)

Ceftriaxone's Analgesic Potential in Formalin-Induced Nociception

This study delves into the intriguing world of pain management, exploring the analgesic properties of ceftriaxone, a commonly prescribed antibiotic. The researchers investigated ceftriaxone's potential to alleviate pain in rats using the formalin-induced nociception test, a model mimicking the pain response in humans. This test involves injecting formalin into the paw, inducing two distinct phases of pain. The researchers found that ceftriaxone effectively attenuated the second phase of pain when administered both locally and systemically. Think of it like a camel finding a cool oasis in the scorching desert of persistent pain. This suggests that ceftriaxone might offer a promising alternative to traditional pain relief strategies, potentially leading to a wider range of therapeutic applications.

Anti-inflammatory Potential of Ceftriaxone

The study’s findings highlight the potential anti-inflammatory effect of ceftriaxone, with a particular focus on the attenuation of the second phase of pain. This is significant because it suggests that ceftriaxone may be a valuable tool for managing chronic pain, which often involves inflammation. It’s like a camel learning to adapt to the harsh desert environment by finding ways to manage the pain and inflammation it experiences.

Potential for Pain Management

The study’s findings offer intriguing possibilities for managing pain, particularly chronic pain, which is a major health concern. If further research confirms the analgesic properties of ceftriaxone, it could potentially offer a new treatment option for those struggling with chronic pain. This could be a revolutionary discovery for those seeking relief from chronic pain, like a desert traveler discovering a life-saving source of water.

Dr.Camel's Conclusion

While more research is needed to determine the full extent of ceftriaxone's analgesic potential, this study suggests that this commonly used antibiotic could offer a novel approach to managing pain. This opens up a new avenue for pain relief, potentially transforming the way we approach chronic pain management.

Date :
  1. Date Completed 2021-09-01
  2. Date Revised 2021-09-01
Further Info :

Pubmed ID

32394536

DOI: Digital Object Identifier

10.1002/ddr.21680

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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