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Electrospun fibers: an innovative delivery method for the treatment of bone diseases.

Author: ChenYu, CuiWenguo, GuanJianzhong, GuanJingjing, MaoYingji, YeTingjun, ZhaoYupeng, ZhouPinghui, ZhuYansong

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Drug-loaded electrospun fibers are a promising material for treating orthopedic injuries due to their 3-dimensional structure, controlled drug release, and high affinity with local tissues. They have potential applications in treating bone and cartilage defects, tendon adhesion, vascular remodeling, skin grafting, and nervous-system injuries.
Paper Details　
Original Abstract of the Article :
The treatment performances of current surgical therapeutic materials for injuries caused by high-energy trauma, such as prolonged bone defects, nerve-fiber disruptions, and repeated spasms or adhesions of vascular tendons after repair, are poor. Drug-loaded electrospun fibers have become a novel pol...See full text at original site
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引用元：
https://doi.org/10.1080/17425247.2020.1767583

データ提供：米国国立医学図書館（NLM）

Electrospun Fibers: A Novel Delivery Method for Bone Disease Treatment

Bone diseases and injuries pose significant challenges in the field of orthopedic surgery. This review explores the potential of electrospun fibers as a novel drug delivery system for treating various orthopedic conditions, such as bone defects, nerve-fiber disruptions, and tendon adhesions. Electrospun fibers offer unique advantages, including their three-dimensional structure, controlled drug release, and high affinity with local tissues. The authors discuss different methods for loading drugs onto electrospun fibers and modifying them to enhance drug permeability and bioavailability. They highlight the promising applications of drug-loaded electrospun fibers in treating a wide range of orthopedic conditions.

Electrospun Fibers: A New Frontier in Bone Regeneration

This review provides a comprehensive overview of the exciting potential of electrospun fibers in the treatment of bone diseases and injuries. The researchers highlight the versatility of this technology, suggesting that it could revolutionize the field of orthopedic surgery by offering new and innovative solutions for bone regeneration and tissue repair. The potential for controlled drug delivery and improved biocompatibility could significantly enhance treatment outcomes for patients.

Bone Disease: A Journey Towards Restoration and Healing

Bone disease and injuries can be likened to cracks in the desert landscape, disrupting the smooth flow of life. This review offers a glimpse into the potential of electrospun fibers as a new tool for restoring and healing these cracks, paving the way for better treatment options for patients. This research, like a desert oasis, offers hope for a brighter future for individuals battling bone-related conditions.

Dr.Camel's Conclusion

This review showcases the potential of electrospun fibers as a revolutionary drug delivery system for bone disease treatment. The unique properties of electrospun fibers could revolutionize the field of orthopedics, offering new possibilities for tissue regeneration and enhanced treatment outcomes. Just as a camel adapts to the harsh desert environment, this technology could revolutionize our approach to bone healing.

Date :
  1. Date Completed 2021-01-12
  2. Date Revised 2021-01-12
Further Info :

Pubmed ID

32394737

DOI: Digital Object Identifier

10.1080/17425247.2020.1767583

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・Effective treatment of bone diseases
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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