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Investigational treatments in phase I and II clinical trials: a systematic review in chronic obstructive pulmonary disease (COPD).

Author: CalzettaLuigino, CazzolaMario, MateraMaria Gabriella, PezzutoGabriella, RitondoBeatrice Ludovica, RoglianiPaola

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review assesses investigational agents in Phase I and II clinical trials for COPD, examining whether these agents offer promising future treatments.
Paper Details　
Original Abstract of the Article :
<b>Introduction</b>. The current pharmacological treatments for the management of stable COPD permit the reduction of symptoms and frequency and severity of exacerbations, and the improvement of exercise tolerance and health status. However, they do not modify the long-term decline in lung function...See full text at original site
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引用元：
https://doi.org/10.1080/13543784.2020.1769064

データ提供：米国国立医学図書館（NLM）

Chronic Obstructive Pulmonary Disease (COPD): A Search for New Horizons

COPD, a chronic lung disease characterized by airflow obstruction, presents a significant challenge for patients and healthcare professionals alike. This research provides a comprehensive review of investigational agents in Phase I and II clinical trials for COPD, highlighting the ongoing search for more effective treatments. The authors discuss the current limitations of existing therapies, emphasizing the need for innovative approaches to address the progressive nature of COPD and improve patient outcomes.

A Quest for Innovation: New Therapies for COPD

This research highlights the ongoing quest for innovative treatments for COPD. The authors' review of investigational agents provides a glimpse into the promising research efforts aimed at addressing this challenging condition. While existing therapies offer symptom management, the need for novel approaches that can modify disease progression and improve long-term outcomes remains paramount.

Navigating the Labyrinth of COPD: Hope for the Future

This research offers a ray of hope for individuals living with COPD, highlighting the ongoing efforts to develop more effective treatments. The authors' review of investigational agents underscores the commitment to improving patient outcomes and finding new ways to combat this complex disease. Open communication with healthcare professionals is essential for discussing treatment options and determining the most appropriate course of action for individual needs.

Dr. Camel's Conclusion

This research provides a comprehensive overview of investigational agents in Phase I and II clinical trials for COPD, highlighting the ongoing search for more effective treatments. The authors' review underscores the need for continued research and development of innovative therapies to address the progressive nature of COPD and improve patient outcomes.

Date :
  1. Date Completed 2021-01-27
  2. Date Revised 2021-01-27
Further Info :

Pubmed ID

32401655

DOI: Digital Object Identifier

10.1080/13543784.2020.1769064

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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