Oxytocin in the dorsal raphe nucleus antagonizes the inhibition of maternal care induced by food deprivation.

Author: FujisakiMotoyuki, IshiiToshiaki, MuroiYoshikage, NakamuraAyane

Paper Details 
Original Abstract of the Article :
Lactation is indispensable for the pup's survival, but is considered a survival burden in dams under negative energy conditions. In the present study, we tested our hypothesis that oxytocin may facilitate energy investment to pups through behavioral control as well as milk ejection. Maternal care wa...See full text at original site
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引用元:
https://doi.org/10.1016/j.yhbeh.2020.104773

データ提供:米国国立医学図書館(NLM)

Oxytocin in the Dorsal Raphe Nucleus: A Key to Understanding Maternal Care

Maternal care is a fundamental instinct, but it can be impacted by various factors, including the mother's nutritional state. This research explores the role of oxytocin, a hormone associated with social bonding and maternal behavior, in regulating maternal care in food-deprived dams. The researchers investigated the effects of oxytocin in the dorsal raphe nucleus (DRN), a brain region involved in regulating energy state and maternal care. They found that oxytocin in the DRN was necessary for maintaining maternal care in food-deprived dams. Their research also indicates that oxytocin may be released from the paraventricular nucleus (PVN) of the hypothalamus and transported to the DRN to regulate maternal care under food-restricted conditions.

Oxytocin's Role in Maternal Care: A Complex Interplay

This study sheds light on the complex interplay between energy state, oxytocin signaling, and maternal behavior. The researchers' findings suggest that oxytocin in the DRN plays a crucial role in regulating maternal care, particularly under conditions of food deprivation. This research provides a valuable contribution to our understanding of the neurobiological mechanisms underlying maternal care and its sensitivity to energy balance.

Understanding the Importance of Maternal Care

Maternal care is essential for the survival and well-being of offspring. This research highlights the importance of supporting mothers and ensuring that they have access to adequate nutrition and resources. Understanding the neurobiological mechanisms underlying maternal care can help develop strategies to promote healthy mother-infant bonding and provide support for mothers facing challenges.

Dr. Camel's Conclusion

Think of oxytocin as a magic sand that can bind a mother camel to her young. This research suggests that when a mother camel is hungry (food-deprived), this magic sand is needed to keep her connected to her baby and provide care. It's a fascinating reminder of the complex interplay between hormones, brain activity, and the fundamental instinct of nurturing offspring.

Date :
  1. Date Completed 2021-05-24
  2. Date Revised 2021-05-24
Further Info :

Pubmed ID

32437716

DOI: Digital Object Identifier

10.1016/j.yhbeh.2020.104773

Related Literature

SNS
PICO Info
in preparation
Languages

English

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