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BOLD activation during cue induced craving in adolescent inhalant users.

Author: DeepRaman, DhawanAnju, JainRaka, JainShobhit, KumaranS Senthil

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Observational StudyResearch that observes and collects data on participants' behavior and outcomes in their natural state, without intervention.

Overview

This study compared brain activity patterns in adolescent inhalant users and healthy controls in response to craving cues. Inhalant users showed increased activation in brain regions associated with visuo-spatial attention, visual perception, working memory, and motivation, while the control group showed activation in the insula. These findings provide insights into the neural mechanisms underlying cue-induced craving in adolescent inhalant users.
Paper Details　
Original Abstract of the Article :
Inhalants are legally available substances, most of them inexpensive, which are often abused by adolescents. Craving causes their continued use and repeated relapses. There is a need to understand the cue-induced craving and the associated neural mechanisms. In absence of any such prior study, the p...See full text at original site
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引用元：
https://doi.org/10.1016/j.ajp.2020.102097

データ提供：米国国立医学図書館（NLM）

Cue-Induced Craving in Adolescent Inhalant Users: A Journey into the Brain

The field of [addiction research] is constantly exploring the neural mechanisms underlying drug craving, a key factor driving continued use and relapse. This study investigates the [brain activation patterns] associated with [cue-induced craving] in [adolescent inhalant users] using [functional magnetic resonance imaging (fMRI)]. The authors compared [BOLD activation] in the brains of [adolescent inhalant users] and [healthy controls] in response to [inhalant-related cues] to understand the neural correlates of craving in this vulnerable population.

Neural Correlates of Craving: A Glimpse into the Desert of Addiction

The study revealed significant differences in [BOLD activation] patterns between [adolescent inhalant users] and [healthy controls] in response to [inhalant-related cues]. The [inhalant users] exhibited increased activation in brain regions associated with [visuo-spatial attention], [visual perception], [working memory], and [motivation]. These findings offer a deeper understanding of the neural mechanisms underlying [cue-induced craving] in [adolescent inhalant users], potentially providing insights into the development of effective interventions for preventing relapse.

Navigating the Shifting Sands of Addiction Treatment

The desert of [addiction treatment] is constantly shifting, with new insights into the complex neural processes that drive craving and relapse. This study sheds light on the unique neural pathways involved in [cue-induced craving] in [adolescent inhalant users]. This understanding is crucial for developing targeted interventions that address the specific neural mechanisms contributing to this challenging aspect of addiction.

Dr.Camel's Conclusion

This study provides valuable insights into the neural underpinnings of [cue-induced craving] in [adolescent inhalant users]. The findings highlight the specific brain regions involved in this process, potentially paving the way for more effective interventions to combat craving and prevent relapse. This research is essential for developing tailored strategies for addressing the unique challenges faced by young people struggling with inhalant addiction.

Date :
  1. Date Completed 2021-06-21
  2. Date Revised 2022-05-31
Further Info :

Pubmed ID

32454423

DOI: Digital Object Identifier

10.1016/j.ajp.2020.102097

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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