Comparative trial of endocrine versus cytotoxic treatment in advanced breast cancer.

Author: BaumM, ForbesJ, JonesV, PriestmanT

Paper Details 
Original Abstract of the Article :
Ninety-two women with advanced breast cancer were allocated at random to receive either cytotoxic or endocrine treatment. Out of 45 women included in the cytotoxic treatment group, 22 (49%) achieved complete or partial remission of their disease, whereas of the 47 included in the endocrine treatment...See full text at original site
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引用元:
https://doi.org/10.1136/bmj.1.6071.1248

データ提供:米国国立医学図書館(NLM)

Endocrine vs. Cytotoxic: A Camel's Tale of Breast Cancer Treatment

The treatment of advanced breast cancer is a complex and challenging journey. This clinical trial explores the efficacy of two distinct treatment approaches: endocrine therapy and cytotoxic therapy. The authors randomly assigned patients to receive either endocrine or cytotoxic treatments and meticulously followed their progress, comparing their response rates and survival times. Their findings revealed significant differences in treatment effectiveness, with cytotoxic therapy showing greater efficacy in premenopausal women, while endocrine therapy with tamoxifen proved equally effective in postmenopausal women with predominantly soft-tissue disease.

Treatment Choices: A Tailored Approach

This clinical trial underscores the need for a tailored approach to breast cancer treatment. The results highlight the importance of considering factors such as menopausal status and disease characteristics when selecting the most appropriate treatment strategy. This research emphasizes the need for individualized care and ongoing research to optimize treatment outcomes for breast cancer patients.

Breast Cancer Treatment: A Constant Evolution

The landscape of breast cancer treatment is constantly evolving, and this clinical trial adds valuable information to our understanding of the effectiveness of different treatment strategies. The findings underscore the need for continued research and exploration of novel therapies. It's important to remember that even in the face of challenging diagnoses, hope and progress remain, driven by the dedication of researchers and clinicians working tirelessly to improve patient outcomes.

Dr.Camel's Conclusion

The treatment of advanced breast cancer is a long and winding road. This clinical trial provides valuable insights into the efficacy of endocrine versus cytotoxic therapies. The findings highlight the need for a tailored approach to treatment, considering individual patient factors and the evolving landscape of breast cancer research. It's encouraging to see ongoing efforts to improve the lives of breast cancer patients, driven by the dedication of researchers and clinicians striving to find new and better treatments.

Date :
  1. Date Completed 1977-07-18
  2. Date Revised 2019-05-01
Further Info :

Pubmed ID

324570

DOI: Digital Object Identifier

10.1136/bmj.1.6071.1248

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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