Elbasvir/grazoprevir is effective and tolerable for the treatment of HCV GT1-infected patients: A real world multicenter observatory study in Taiwan.

Author: ChenChi-Yi, ChengPin-Nan, LinChun-Che, LinChun-Yen, LiuChun-Jen, LoChing-Chu, PengCheng-Yuan, TsengI-Hao, TsengKuo-Chih, YuMing-Lung

Paper Details 
Original Abstract of the Article :
BACKGROUND & AIMS: Treatment of hepatitis C virus (HCV) by elbasvir/grazoprevir (EBR/GZR) was found to be efficacious and well tolerated in clinical trials. This study aimed to evaluate the effectiveness and tolerability of EBR/GZR in the treatment of HCV genotype 1-infected Taiwanese patients. MET...See full text at original site
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引用元:
https://doi.org/10.1016/j.jmii.2020.05.004

データ提供:米国国立医学図書館(NLM)

Elbasvir/grazoprevir: A Powerful Weapon Against HCV Genotype 1

Hepatitis C virus (HCV) infection is a serious public health concern, potentially leading to liver disease and complications. This study investigates the effectiveness and tolerability of elbasvir/grazoprevir (EBR/GZR), a direct-acting antiviral combination therapy, in treating patients with HCV genotype 1 infection. The authors conducted a real-world, multicenter observational study in Taiwan, analyzing the treatment outcomes of patients with HCV genotype 1 who received EBR/GZR for 12 weeks. They assessed the sustained virologic response (SVR) rates, which indicate the long-term suppression of the virus, and the safety profile of the treatment.

EBR/GZR: A Promising Therapy for HCV Genotype 1

The study's findings demonstrate the high efficacy and tolerability of EBR/GZR in treating HCV genotype 1 infection. The authors observed a remarkable SVR12 rate of 99.5%, indicating that the treatment was highly effective in achieving long-term viral suppression. Furthermore, the treatment was well tolerated, with only a small percentage of patients experiencing adverse events. These results suggest that EBR/GZR is a safe and effective treatment option for HCV genotype 1 infection.

Addressing HCV: A Multifaceted Approach

This research underscores the importance of developing effective and well-tolerated treatments for HCV infection. By utilizing direct-acting antiviral agents like EBR/GZR, healthcare providers can effectively manage HCV infection and prevent its potentially serious consequences. This study encourages continued research and development of innovative therapies to combat HCV and improve patient outcomes.

Dr. Camel's Conclusion

This research shines a light on the remarkable advancements in antiviral therapies. Just as a desert oasis provides a source of life-sustaining water, effective treatments for HCV infection offer hope and healing for patients. This study's findings demonstrate the power of modern medicine in combating infectious diseases and improving the lives of individuals around the world.

Date :
  1. Date Completed 2021-12-16
  2. Date Revised 2021-12-16
Further Info :

Pubmed ID

32499107

DOI: Digital Object Identifier

10.1016/j.jmii.2020.05.004

Related Literature

SNS
PICO Info
in preparation
Languages

English

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