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Pharmacometabolomics with a combination of PLS-DA and random forest algorithm analyses reveal meloxicam alters feline plasma metabolite profiles.
Author: Broughton-NeiswangerLiam E, HwangJulianne K, Rivera-VelezSol M, SlovakJennifer E, SuarezMartin A, VillarinoNicolas F
Original Abstract of the Article :
Repeated administration of meloxicam to cats is often limited by the potential damage to multiple organ systems. Identifying molecules that predict the adverse effects of meloxicam would help to monitor and individualize its administration, maximizing meloxicam's beneficial effects. The objectives o...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/jvp.12884
データ提供:米国国立医学図書館(NLM)
Unveiling the Secrets of Meloxicam in Feline Medicine
This research delves into the fascinating world of pharmacometabolomics, using advanced technology to understand how medications affect the body at a molecular level. It's like using a sophisticated microscope to examine the intricate workings of a desert ecosystem, revealing hidden pathways and connections.
The study focuses on meloxicam, a common pain reliever used in veterinary medicine. The researchers investigated how repeated administration of meloxicam affects feline plasma metabolite profiles. It's like studying the impact of a desert storm on the composition of soil, uncovering the intricate web of interactions that govern biological processes.
A New Perspective on Drug Effects
The study discovered that meloxicam alters the composition of various substances in feline plasma, including organic acids, amino acids, and inorganic compounds. This is like finding a new and unexpected pattern in the sand dunes, revealing the potential for unexpected consequences of medication use.
Personalized Medicine for Feline Patients
The research highlights the potential for using metabolomics to monitor and personalize the administration of meloxicam in cats, minimizing adverse effects and maximizing therapeutic benefits. It's like using a combination of tools and techniques to manage a desert garden, ensuring the optimal growth and well-being of the plants.
Dr.Camel's Conclusion
This research offers a unique perspective on drug effects, revealing the hidden complexities of medication interactions at a molecular level. It's like exploring a vast and intricate desert landscape, uncovering new pathways for understanding and managing medication use in animals.
Date :
- Date Completed 2021-05-18
- Date Revised 2021-05-18
Further Info :
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English
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