Effectiveness, tolerability, and dropout rates of vortioxetine in comorbid depression: A naturalistic study.

Author: BenattiBeatrice, BosiMonica Francesca, ColomboAnna, De CarloVera, Dell'OssoBernardo, GranciniBenedetta, ViganòCaterina Adele, VismaraMatteo

Paper Details 
Original Abstract of the Article :
OBJECTIVE: Vortioxetine is a novel antidepressant whose safety, tolerability, and therapeutic action have been supported by several studies. The present naturalistic study aimed to characterize its effectiveness, tolerability, and dropout rate in the real world. METHODS: Total sample consisted of 6...See full text at original site
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引用元:
https://doi.org/10.1002/hup.2750

データ提供:米国国立医学図書館(NLM)

Vortioxetine: A New Oasis for Comorbid Depression

Vortioxetine, a novel antidepressant, has shown promise in treating major depressive disorder. This naturalistic study investigated its effectiveness, tolerability, and dropout rate in real-world settings, particularly among patients with comorbid depression. Researchers analyzed clinical data from 66 outpatients treated with vortioxetine, assessing their response to treatment, side effects, and reasons for discontinuation.

Vortioxetine's Performance: A Mixed Bag in the Desert of Comorbid Depression

The study found that vortioxetine was associated with significant improvements in specific psychometric scales, indicating its potential effectiveness in treating comorbid depression. However, the study also revealed a high dropout rate, primarily due to side effects and lack of efficacy.

Navigating the Landscape: Understanding the Trade-offs

This study, like a caravan navigating a vast and unpredictable desert, highlights the complex nature of treating comorbid depression. The study's findings suggest that vortioxetine may offer a valuable treatment option for some patients, but it is crucial to consider the potential side effects and the risk of treatment discontinuation.

Dr. Camel's Conclusion

This naturalistic study, like a well-stocked oasis in the desert of comorbid depression, offers valuable insights into the effectiveness and tolerability of vortioxetine. The study highlights the need for careful consideration of potential side effects and patient response when prescribing this medication.

Date :
  1. Date Completed 2021-09-14
  2. Date Revised 2021-09-14
Further Info :

Pubmed ID

32662933

DOI: Digital Object Identifier

10.1002/hup.2750

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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