Fourteen small molecule and biological agents for psoriatic arthritis: A network meta-analysis of randomized controlled trials.

Author: GaoWenjuan, QiuMingliang, WenXianhua, XiongMeizhen, XuZhongbo, YuMinfeng, ZhouXu, ZhuWeina

Paper Details 
Original Abstract of the Article :
BACKGROUND: The comparative efficacy and safety of small molecule and biological agents in the treatment of psoriatic arthritis (PsA) remain unknown. OBJECTIVES: To compare the efficacy and safety of 14 small molecule and biological agents by network meta-analysis (NMA). METHODS: Relevant randomiz...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402795/

データ提供:米国国立医学図書館(NLM)

A Multifaceted Approach to Psoriatic Arthritis: Small Molecules and Biologics

This study delves into the world of psoriatic arthritis (PsA), a chronic inflammatory condition that affects both the joints and the skin. The researchers conducted a comprehensive network meta-analysis to compare the efficacy and safety of 14 different small molecule and biological agents used to treat PsA. Their findings, like a well-mapped oasis in the desert, provide valuable insights into the relative effectiveness and safety of various treatment options, helping patients and healthcare providers make informed decisions about treatment approaches.

Navigating the Treatment Landscape: A Guide to PsA Therapies

The researchers found that several biologics, such as etanercept, infliximab, and secukinumab, were more effective than placebo in achieving improvements in PsA symptoms. However, they also found that all medications, except secukinumab, had comparable safety profiles to placebo. These findings, like a compass guiding a traveler through the desert, provide valuable information for patients and healthcare providers to select the most appropriate treatment based on individual needs and risks. The study also highlighted the importance of considering both efficacy and safety when choosing a treatment for PsA.

Managing PsA: A Long and Winding Road

Psoriatic arthritis, like a challenging desert trek, can be a long and often arduous journey. This study serves as a valuable guidepost, offering insights into the relative benefits and risks of different treatment options. By understanding the comparative efficacy and safety of various therapies, patients and healthcare providers can work together to navigate this challenging condition and find the most effective path towards managing symptoms and improving quality of life.

Dr.Camel's Conclusion

This study offers a comprehensive overview of the treatment landscape for psoriatic arthritis, a condition as complex as the shifting dunes of the desert. The researchers' thorough analysis provides valuable insights into the relative efficacy and safety of various treatment options, guiding patients and healthcare providers towards more effective and personalized care. This research highlights the importance of carefully considering both efficacy and safety when choosing a treatment for PsA.

Date :
  1. Date Completed 2020-08-17
  2. Date Revised 2022-10-05
Further Info :

Pubmed ID

32756163

DOI: Digital Object Identifier

PMC7402795

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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