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Effect of D-Cycloserine on the Effect of Concentrated Exposure and Response Prevention in Difficult-to-Treat Obsessive-Compulsive Disorder: A Randomized Clinical Trial.

Author: AbramowitzJonathan S, BørtveitTore, CraskeMichelle G, FranklinMartin E, HagenKristen, HansenBjarne, HasethSvein, HimleJoseph A, HystadSigurd, KristensenUnn Beate, KvaleGerd, LaunesGunvor, LundAnders, SolemStian, ÖstLars-Göran

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

There aren't many effective treatments for people with severe OCD. Some experts believe that a medication called D-cycloserine (DCS) could make exposure and response prevention (ERP) therapy more effective, but this hasn't been tested in people with severe OCD.
Paper Details　
Original Abstract of the Article :
Evidence is lacking for viable treatment options for patients with difficult-to-treat obsessive-compulsive disorder (OCD). It has been suggested that D-cycloserine (DCS) could potentiate the effect of exposure and response prevention (ERP) treatment, but the hypothesis has not been tested among pati...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426745/

データ提供：米国国立医学図書館（NLM）

D-Cycloserine: A Potential Booster for OCD Treatment?

This randomized clinical trial explores the potential benefits of combining D-cycloserine (DCS) with exposure and response prevention (ERP) therapy for treating difficult-to-treat obsessive-compulsive disorder (OCD). It's like a scientific experiment, where researchers are testing a new combination therapy to combat the persistent challenges of OCD. The researchers hypothesized that DCS could potentiate the effects of ERP, making it more effective for those with difficult-to-treat OCD. It's like adding a catalyst to a chemical reaction, boosting the effectiveness of ERP therapy.

A Novel Approach to OCD Treatment

The researchers are looking for new ways to help patients with OCD who have not responded well to traditional therapies. It's like searching for a hidden oasis in the vast desert of OCD treatment. By exploring the potential of DCS to enhance the effectiveness of ERP, they are opening up new possibilities for those struggling with this debilitating condition.

Hope for a Better Future: Unlocking the Potential of Combination Therapies

This study represents a promising step forward in the treatment of OCD. It's like a ray of hope in the desert, suggesting that new and innovative therapies might hold the key to improving the lives of individuals struggling with OCD. By exploring the potential of combination therapies, we may be able to find more effective and personalized treatments for those with OCD.

Dr.Camel's Conclusion

This clinical trial investigates the potential of D-cycloserine to enhance the effectiveness of ERP therapy for difficult-to-treat OCD. It's like a desert traveler, seeking new ways to navigate the challenging terrain of OCD and find a path to healing. By exploring new treatment options, we can offer hope and support to those struggling with this complex condition. It's a reminder that the search for effective treatments is an ongoing journey, and we must continue to explore new possibilities to improve the lives of individuals with OCD.

Date :
  1. Date Completed 2021-01-04
  2. Date Revised 2021-01-04
Further Info :

Pubmed ID

32789516

DOI: Digital Object Identifier

PMC7426745

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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