Decrease in LDL and increase in HDL concentrations in type II hyperlipoproteinaemic patients on low-dose combination therapy of cholestyramine and Complamin.

Author: FearsR, FerresH, HaackeH, MäderC, ParwareschM R

Paper Details 
Original Abstract of the Article :
A low-dose combination of Complamin retard (1 g t.i.d.) and cholestyramine (4 g b.i.d.) was compared with each agent alone in 2 serial open trials without dietary restriction using type IIa and IIb hyperlipoproteinaemic patients. Complamin alone produced decreases in LDL and VLDL cholesterol concent...See full text at original site
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引用元:
https://doi.org/10.1016/0021-9150(88)90001-9

データ提供:米国国立医学図書館(NLM)

Cholestyramine and Complamin: A Winning Combination for Type II Hyperlipoproteinemia

In the vast desert of cardiovascular disease, researchers are constantly seeking strategies to control lipid levels. This study explored the combined effects of cholestyramine and Complamin, two medications commonly used to manage type II hyperlipoproteinemia. Like a wise camel carefully selecting its route, the researchers conducted two open trials comparing the combination therapy to each agent alone. Their findings revealed that the combination therapy produced marked and progressive reductions in total cholesterol and LDL cholesterol, effectively clearing a path for better lipid profiles.

A Comprehensive Approach to Lipid Management

The study provides compelling evidence that combining cholestyramine and Complamin offers a more comprehensive approach to managing type II hyperlipoproteinemia. The combination therapy outperformed the individual agents in reducing lipid levels, suggesting a synergistic effect that could significantly benefit patients.

Good News for Cardiovascular Health

The results of this study offer hope for patients with type II hyperlipoproteinemia, a condition that increases the risk of heart disease. By effectively lowering lipid levels, the combination therapy could contribute to reducing the risk of cardiovascular events, paving the way for a healthier journey.

Dr.Camel's Conclusion

This study serves as a reminder that, just as the desert provides different resources depending on the location, different approaches may be necessary to address complex health conditions. The combination of cholestyramine and Complamin presents a promising strategy for managing type II hyperlipoproteinemia, offering a glimpse of a healthier future for those affected.

Date :
  1. Date Completed 1988-04-18
  2. Date Revised 2019-07-18
Further Info :

Pubmed ID

3279969

DOI: Digital Object Identifier

10.1016/0021-9150(88)90001-9

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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