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Prevalence and characteristics of HIV drug resistance among antiretroviral treatment (ART) experienced adolescents and young adults living with HIV in Ndola, Zambia.

Author: AbramsElizabeth, BurkeVirginia M, DenisonJulie A, FrimpongChristiana, HandemaRay, KalibalaSam, MitiSam, MulengaLloyd, MwakazangaDavid, MwansaJonathan K, SiwingwaMpanji, ZuluMangani

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.

Overview

This abstract highlights the threat of HIV drug resistance (HIVDR) in Zambia, particularly among youth aged 15-24 years. Understanding the prevalence and patterns of HIVDR in this population is crucial for defining effective ART regimens, improving clinical decision-making, and supporting behavioral change interventions.
Paper Details　
Original Abstract of the Article :
HIV drug resistance (HIVDR) poses a threat to the HIV epidemic control in Zambia especially in sub-populations such as the 15-24 years where there is poor virological suppression. Understanding the prevalence and patterns of HIVDR in this population (15-24 years) will contribute to defining effectiv...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430722/

データ提供：米国国立医学図書館（NLM）

HIV Drug Resistance: A Persistent Challenge in Zambia

The fight against HIV is a global effort, and understanding the evolving nature of the virus is crucial for developing effective treatment strategies. This study focused on HIV drug resistance (HIVDR) among adolescents and young adults living with HIV in Ndola, Zambia. Researchers investigated the prevalence and characteristics of HIVDR in this specific population, recognizing that drug resistance can hinder the effectiveness of antiretroviral therapy (ART) and impact the overall success of HIV control programs.

Addressing Drug Resistance: A Crucial Step in HIV Control

The study found that HIVDR is a significant challenge, particularly among adolescents and young adults, and can be attributed to factors like poor virological suppression. This study highlights the importance of early detection and intervention to prevent the development of HIVDR and ensure the effectiveness of ART. It's like a desert caravan facing a sandstorm – prompt action and strategic adjustments are crucial for navigating the challenges and reaching the desired destination.

Improving ART Regimens and Supporting Behavioral Change: A Path to Success

This study emphasizes the need for continuous monitoring and refinement of ART regimens to effectively combat HIVDR. Researchers also highlight the importance of behavioral change interventions to promote adherence to ART and minimize the risk of drug resistance. It's like navigating a vast desert, requiring consistent vigilance and strategic planning to overcome obstacles and achieve a successful outcome.

Dr.Camel's Conclusion

This study sheds light on the ongoing challenge of HIV drug resistance, particularly among adolescents and young adults in Zambia. It underscores the need for comprehensive efforts to improve ART regimens, promote adherence, and address the behavioral factors that contribute to drug resistance. By working together, we can create a more effective path to managing HIV and improving the lives of individuals affected by this virus.

Date :
  1. Date Completed 2020-10-01
  2. Date Revised 2021-02-17
Further Info :

Pubmed ID

32804970

DOI: Digital Object Identifier

PMC7430722

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Languages

English

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