Psychosis relapse during treatment with long-acting injectable antipsychotics in individuals with schizophrenia-spectrum disorders: an individual participant data meta-analysis.

Author: CorrellChristoph U, GuinartDaniel, JohnMajnu, KaneJohn M, MalhotraAnil K, RubioJose M, SchoretsanitisGeorgios, TaipaleHeidi, TiihonenJari

Paper Details 
Original Abstract of the Article :
Most individuals with schizophrenia-spectrum disorders have relapses, which increase the risk of morbidity and mortality. Because non-adherence to antipsychotic maintenance treatment could affect more than half of individuals with schizophrenia-spectrum disorders, psychosis relapse can often be conf...See full text at original site
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引用元:
https://doi.org/10.1016/S2215-0366(20)30264-9

データ提供:米国国立医学図書館(NLM)

Relapse During Long-Acting Injectable Antipsychotics in Schizophrenia-Spectrum Disorders: A Meta-Analysis

The world of mental health is constantly striving for better understanding and treatments for complex disorders like schizophrenia-spectrum disorders. This meta-analysis delves into the critical issue of psychosis relapse in individuals with schizophrenia-spectrum disorders, even during treatment with long-acting injectable antipsychotics. By combining data from multiple studies, the researchers aim to generate reliable estimates of relapse incidence and identify potential predictors of relapse during assured antipsychotic treatment.

Understanding Relapse: A Complex Challenge

This meta-analysis sheds light on the complex nature of relapse in schizophrenia-spectrum disorders. The researchers found that relapse can occur even during confirmed antipsychotic treatment, highlighting the need for comprehensive management strategies that go beyond medication adherence. Identifying predictors of relapse is crucial for tailoring treatment plans and proactively addressing individual risk factors.

Navigating Schizophrenia-Spectrum Disorders: A Multifaceted Approach

This research underscores the importance of a multifaceted approach to managing schizophrenia-spectrum disorders. The findings highlight the need for comprehensive treatment plans that address not only medication adherence but also individual risk factors for relapse. These strategies might include psychosocial interventions, support groups, and close monitoring to ensure optimal patient outcomes. Imagine this process as a journey through a vast and unforgiving desert, where a combination of medication, therapy, and support creates a sustainable path towards recovery and well-being.

Dr.Camel's Conclusion

This meta-analysis provides valuable insights into the complexities of psychosis relapse in schizophrenia-spectrum disorders, even during antipsychotic treatment. The findings underscore the need for comprehensive management strategies that address both medication adherence and individual risk factors. This research serves as a reminder that the journey towards recovery from schizophrenia-spectrum disorders requires a collaborative effort, involving patients, families, and healthcare providers, all working together to navigate the challenging landscape of mental health.

Date :
  1. Date Completed 2020-09-02
  2. Date Revised 2020-09-02
Further Info :

Pubmed ID

32828165

DOI: Digital Object Identifier

10.1016/S2215-0366(20)30264-9

Related Literature

SNS
PICO Info
in preparation
Languages

English

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