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Simvastatin-loaded nanoemulsions: development, characterization, stability study and toxicity assays.

Author: Antunes SoaresFélix Alexandre, BoeckCarina Rodrigues, BudelRenata Gancine, Fontanari KrauseLuciana Maria, GuerinoBruna Costabeber, MachadoMarina Lopes, MoreiraMichele Pereira, OuriqueAline Ferreira, WergutzJulien

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study aimed to prepare and characterize simvastatin-loaded nanoemulsions (SIM-LN) and evaluate their physicochemical properties and toxicity. The SIM-LN demonstrated high encapsulation rate and no toxicity in preliminary tests.
Paper Details　
Original Abstract of the Article :
<b>Aim:</b> The aim of this study is to prepare and characterize simvastatin-loaded nanoemulsions (SIM-LN) as well as evaluate their physicochemical properties and toxicity. <b>Methodology &amp; results:</b> The SIM-LN were prepared, their characteristics evaluated for 30&#160;days, and after that,...See full text at original site
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引用元：
https://doi.org/10.4155/tde-2020-0067

データ提供：米国国立医学図書館（NLM）

Simvastatin-Loaded Nanoemulsions: A Safe and Effective Delivery System

Simvastatin, a widely prescribed cholesterol-lowering drug, plays a crucial role in managing cardiovascular health. This research explores the development and characterization of simvastatin-loaded nanoemulsions (SIM-LN), a novel drug delivery system that aims to improve the efficacy and safety of simvastatin. The researchers successfully developed SIM-LN with optimal properties, demonstrating their potential as a safe and effective drug delivery platform.

Nanoemulsions: A Promising Approach to Drug Delivery

This research highlights the potential of nanoemulsions as a promising platform for drug delivery, particularly for simvastatin. The study demonstrated that SIM-LN can effectively encapsulate simvastatin, ensuring its safe and controlled release within the body.

A New Frontier in Drug Delivery: Nanotechnology

Nanotechnology is rapidly emerging as a powerful tool in drug delivery, offering the potential to improve drug efficacy, reduce side effects, and enhance patient outcomes. The development of SIM-LN represents a significant step forward in this field, showcasing the potential of nanotechnology to revolutionize drug delivery and improve healthcare.

Dr. Camel's Conclusion

Just as a camel can traverse long distances in the desert by carefully storing water, drug delivery systems like nanoemulsions can efficiently transport medications throughout the body. This research demonstrates the potential of SIM-LN in improving simvastatin delivery, contributing to better cardiovascular health. Remember, research in drug delivery continues to evolve, bringing us closer to safer and more effective ways to manage health conditions.
Date :
  1. Date Completed n.d.
  2. Date Revised 2023-04-11
Further Info :

Pubmed ID

32842914

DOI: Digital Object Identifier

10.4155/tde-2020-0067

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SNS
PICO Info
in preparation
Languages

English

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