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Effects of atazanavir, darunavir, and raltegravir on fat and muscle among persons living with HIV.

Author: AdrianStefan, BeghettoBarbara, ErlandsonKristine M, FengHan, GuaraldiGiovanni, LakeJordan E, LigabueGuido, MiaoHongyu, MilicJovana, NardiniGiulia, RoncagliaEnrica, ScherzingerAnn

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Observational StudyResearch that observes and collects data on participants' behavior and outcomes in their natural state, without intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study compares fat and muscle density among people with HIV on different antiretroviral therapies (ARTs), exploring implications for muscle function.
Paper Details　
Original Abstract of the Article :
Label="BACKGROUND">Antiretroviral therapy (ART) is associated with gain in <i>quantity</i> of fat and muscle, but the impact on <i>quality</i> is less understood. The objective of this study was to compare fat and muscle density among people with HIV (PWH) on stable raltegravir (RAL), atazanavir wit...See full text at original site
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引用元：
https://doi.org/10.1080/25787489.2020.1809807

データ提供：米国国立医学図書館（NLM）

Antiretroviral Therapy: Impact on Fat and Muscle in HIV Patients

Antiretroviral therapy (ART) has revolutionized the treatment of HIV, significantly improving the lives of people living with the virus. This study examines the impact of ART on fat and muscle composition in HIV patients, focusing on the potential changes in both quantity and quality of these tissues. The researchers compared the effects of three different ART regimens - raltegravir (RAL), atazanavir with ritonavir (ATV/r), and darunavir with ritonavir (DRV/r) - to assess their impact on body composition and muscle function.

ART: A Double-Edged Sword?

The study revealed that while ART can lead to an increase in fat and muscle mass, it can also impact the quality of these tissues. This finding highlights the complex interplay between ART and body composition in HIV patients. Further research is needed to understand the long-term implications of these changes on overall health and well-being.

Maintaining Optimal Health: A Holistic Approach

This research emphasizes the importance of monitoring body composition and muscle function in HIV patients undergoing ART. Healthcare providers should work closely with patients to ensure they are receiving appropriate care and support to maintain optimal health. Just like a camel adapts to the harsh desert environment, HIV patients need to adapt to the complexities of ART and work with their healthcare teams to manage potential side effects and optimize their health.

Dr.Camel's Conclusion

This study underscores the importance of understanding the long-term effects of ART on body composition in HIV patients. By monitoring these changes and providing appropriate support, healthcare providers can help patients maintain optimal health and well-being. Remember, just like a camel navigates the desert with a keen understanding of its environment, HIV patients need to navigate the complexities of ART with the support of their healthcare team.

Date :
  1. Date Completed 2021-08-05
  2. Date Revised 2021-08-05
Further Info :

Pubmed ID

32878571

DOI: Digital Object Identifier

10.1080/25787489.2020.1809807

Related Literature

Article Analysis
・Effects of raltegravir・Effects of darunavir
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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