Comparative effectiveness and safety of intravesical instillation treatment of interstitial cystitis/bladder pain syndrome: a systematic review and network meta-analysis of randomized controlled trials.

Author: LiuShengzhuo, LuYiping, LuoDeyi, PengLiao, ZhangChi

Paper Details 
Original Abstract of the Article :
INTRODUCTION AND HYPOTHESIS: A large variety of agents are available for intravesical instillation treatment of interstitial cystitis/bladder pain syndrome (IC/BPS). The purpose of the study was to compare the efficacy and safety of those agents. METHODS: PubMed, the Cochrane Library, and Embase we...See full text at original site
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引用元:
https://doi.org/10.1007/s00192-020-04490-3

データ提供:米国国立医学図書館(NLM)

Intravesical Instillation: A Mosaic of Treatment Options for Interstitial Cystitis

[Interstitial cystitis/bladder pain syndrome (IC/BPS)] is a chronic condition that can cause debilitating pain and discomfort. Imagine a desert oasis where the water source is polluted, causing irritation and pain – that's what IC/BPS can feel like, impacting the bladder and affecting quality of life. This study explores the effectiveness and safety of various [intravesical instillation] treatments for this condition.

A Network Meta-Analysis of Intravesical Treatments

The study, a [systematic review and network meta-analysis], compares the efficacy and safety of different [intravesical instillation] agents for treating [IC/BPS]. The researchers found that [0.1 μM resiniferatoxin] was more effective than other therapies, while [chondroitin sulphate] appeared to be the safest option. Think of it as exploring different desert oases – each offering unique characteristics and potential benefits, but some may be more effective or safer than others.

Finding the Right Oasis for IC/BPS Treatment

This research provides valuable insights into the diverse landscape of IC/BPS treatment options. The study's findings can help guide clinicians in choosing the most appropriate [intravesical instillation] therapy for their patients. Just as a desert traveler might seek the oasis that best suits their needs, individuals with IC/BPS can work with their healthcare providers to explore different treatment options and find the one that provides the most relief and improvement.

Dr.Camel's Conclusion

This systematic review and network meta-analysis provides valuable information for clinicians treating interstitial cystitis/bladder pain syndrome. While [0.1 μM resiniferatoxin] appears to be the most effective treatment option, the study also highlights the importance of considering individual patient factors and potential risks when choosing therapy. Remember, the journey through IC/BPS treatment can be challenging, but by exploring different options and working closely with healthcare professionals, individuals can find the right oasis of relief and improve their quality of life.

Date :
  1. Date Completed 2021-07-05
  2. Date Revised 2022-05-31
Further Info :

Pubmed ID

32886173

DOI: Digital Object Identifier

10.1007/s00192-020-04490-3

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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