Use of bromelain in cutaneous wound healing in streptozocin-induced diabetic rats: an experimental model.

Author: BabaeiSaeid, BabaeiSepehr, BabaeiSoroush, FathiAmene Nikgoftar, SakhaieMohammad Hassan, SlimabadFateme

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To assess the effect of bromelain on different aspects of the wound healing process in type 1 diabetic rats. METHOD: In this study, 112 streptozocin-diabetic (type 1) male Wistar rats were euthanised; 28 each on days three, five, seven and 15, after a wound incision had been made. To est...See full text at original site
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引用元:
https://doi.org/10.12968/jowc.2020.29.9.488

データ提供:米国国立医学図書館(NLM)

Bromelain: A Potential Ally in Wound Healing for Diabetic Patients

Diabetic patients often face a unique challenge when it comes to wound healing. Their impaired blood sugar control can delay the body's natural repair processes, leading to complications and prolonged healing times. This research investigates the potential of bromelain, a natural enzyme derived from pineapple, as a therapeutic agent to accelerate wound healing in diabetic rats. The study utilized a streptozocin-induced diabetic rat model to assess the effects of bromelain on various aspects of the wound healing process. The researchers carefully analyzed histological sections of wound tissue at different time points to evaluate the impact of bromelain on cellular and tissue elements, including granulation tissue formation, neovascularization, fibroblast proliferation, and macrophage activity.

Bromelain: A Catalyst for Wound Healing in Diabetic Rats

The findings revealed that bromelain significantly accelerated wound contraction, promoted neovascularization, and increased fibroblast activity in diabetic rats, suggesting its potential to enhance wound healing. Additionally, the study found that bromelain significantly reduced the number of macrophages and epithelial thickness, suggesting its ability to modulate inflammatory responses. This suggests that bromelain might be a valuable tool in promoting faster and more efficient wound healing in diabetic patients.

Harnessing the Healing Power of Bromelain

This research suggests that bromelain may offer a natural and effective way to support wound healing in diabetic patients. While further research is needed to confirm these findings in human patients, the study provides a promising foundation for exploring the therapeutic potential of bromelain in wound care. Just as a desert plant draws strength from the harsh environment to thrive, bromelain may offer a natural solution to the challenges faced by diabetic patients when it comes to wound healing.

Dr.Camel's Conclusion

This research sheds light on the potential of bromelain as a natural therapeutic agent for enhancing wound healing in diabetic patients. While further research is needed to confirm these findings in human patients, the study suggests that bromelain may offer a valuable tool to support faster and more efficient wound healing. It's a reminder that nature holds many secrets to healing, just as a desert oasis provides solace and sustenance in the face of adversity.

Date :
  1. Date Completed 2021-07-01
  2. Date Revised 2022-04-16
Further Info :

Pubmed ID

32924815

DOI: Digital Object Identifier

10.12968/jowc.2020.29.9.488

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SNS
PICO Info
in preparation
Languages

English

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