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Ferritin versus ferrous sulphate preparations: a controlled study in sideropaenic patients.

Author: BräuerH, CeccarelliG, SchefferK, SchreiberG, SásG

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study compared the effectiveness of two different iron supplements: ferrous sulfate (bivalent iron) and ferritin (trivalent iron) in 54 patients who needed iron treatment. Both forms of iron improved blood values, but the improvement was more consistent and progressive with the ferritin preparations. The study concludes that ferritin is an effective treatment option for iron deficiency, likely due to its more natural and physiological form of iron.
Paper Details　
Original Abstract of the Article :
A double-blind study was carried out in 54 patients requiring iron therapy to compare the effects of orally administered bivalent and trivalent iron over a period of 12 weeks. Patients were allocated at random to receive ferrous sulphate (100 mg/day), ferritin (80 mg/day as Fe3+) or a combination of...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/3299394

データ提供：米国国立医学図書館（NLM）

Ferritin vs. Ferrous Sulfate: A Battle in the Iron Desert

This research is like a desert traveler comparing different routes for obtaining essential resources, in this case, iron. The authors conducted a double-blind study comparing the efficacy of orally administered ferrous sulfate and ferritin in patients with iron deficiency. The study found that both iron preparations were effective, but ferritin showed more consistent and progressive improvement in hematological parameters.

Ferritin Emerges as a Superior Iron Source

This research suggests that ferritin may be a more efficient and effective way to deliver iron to patients with iron deficiency. The study found that ferritin led to more consistent and rapid improvements in hematological parameters compared to ferrous sulfate. This finding could potentially lead to better treatment outcomes for patients with iron deficiency anemia.

Exploring New Avenues for Iron Supplementation

This study highlights the importance of exploring different approaches to iron supplementation. The researchers demonstrated that ferritin, a naturally occurring iron-storage protein, may offer a superior alternative to traditional ferrous sulfate preparations. This finding could potentially lead to improved patient outcomes and a more effective approach to managing iron deficiency.

Dr.Camel's Conclusion

This research is like a desert traveler discovering a new and more efficient route to a vital oasis of iron. Ferritin emerges as a promising alternative to traditional iron supplements, offering a potentially more effective and well-tolerated approach to managing iron deficiency.

Date :
  1. Date Completed 1987-07-29
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

3299394

DOI: Digital Object Identifier

3299394

Related Literature

Article Analysis
・Effective treatment of iron
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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