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Calcium-channel-blocking agent in the treatment of acute alcohol withdrawal--caroverine versus meprobamate in a randomized double-blind study.

Author: EberhardtG, HallerR, KoppiS, KönigP

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Caroverine, a group B Ca2+ channel blocker, was found to be as effective as meprobamate in treating alcohol withdrawal symptoms in 22 patients. Caroverine was associated with less sedation than meprobamate, and may be a better choice for treatment.
Paper Details　
Original Abstract of the Article :
We present a randomized double-blind study on the efficacy of caroverine in the treatment of alcohol withdrawal symptoms. The group B Ca2+ channel blocking agent caroverine was tested against meprobamate in inpatient treatment of alcohol withdrawal. Patients of both groups were similar in age, weigh...See full text at original site
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引用元：
https://doi.org/10.1159/000118340

データ提供：米国国立医学図書館（NLM）

The Efficacy of Ca2+ Channel Blockers in Alcohol Withdrawal

I'm Dr. Camel, and I'm always seeking oasis in the vast desert of medical knowledge. This research dives deep into the parched landscape of alcohol withdrawal, a condition that can be as challenging as navigating a sandstorm. This particular study focuses on the effectiveness of caroverine, a Ca2+ channel blocker, as a treatment for alcohol withdrawal symptoms. It's like finding a hidden spring in the desert – a potential solution to a persistent problem. The study compared caroverine with meprobamate, a well-established drug for this condition, in a randomized double-blind trial. Both drugs were found to be equally effective in reducing alcohol withdrawal symptoms. However, caroverine was found to have fewer sedative side effects, making it a more appealing option for some patients. It's like finding a cool breeze in the desert – a treatment that provides relief without making you feel drowsy and sluggish.

Caroverine: A Promising Treatment for Alcohol Withdrawal

This research suggests that caroverine could be a valuable alternative to meprobamate for treating alcohol withdrawal. The results are encouraging, especially the finding that caroverine is less sedative than meprobamate. It's like finding a path through the desert that leads to a more comfortable and pleasant journey.

Navigating Alcohol Withdrawal

This research highlights the need to find effective and well-tolerated treatments for alcohol withdrawal. While caroverine shows promise, it's important to remember that the desert of alcohol withdrawal is complex and each individual's journey will be different. It's crucial to work with a healthcare professional who can help you navigate this challenging terrain.

Dr.Camel's Conclusion

Caroverine may be a good alternative to meprobamate for the treatment of alcohol withdrawal. The results of this study suggest that it is a potentially effective and well-tolerated treatment, offering a more comfortable experience for patients. As a researcher, I find this a promising development in the field of alcohol withdrawal treatment. It's like finding a new oasis in the desert, offering a haven for those seeking relief.
Date :
  1. Date Completed 1987-10-19
  2. Date Revised 2017-11-01
Further Info :

Pubmed ID

3306440

DOI: Digital Object Identifier

10.1159/000118340

Related Literature

Article Analysis
・Side Effects of meprobamate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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