A phase 3 multicenter open-label maintenance study to investigate the long-term safety of sodium zirconium cyclosilicate in Japanese subjects with hyperkalemia.

Author: HaradaHiromasa, KashiharaNaoki, KimHyosung, OsonoiTakeshi, SaraiNobuaki, ShibagakiYugo, YajimaToshitaka, YamasakiYoshimitsu, ZhaoJune

Paper Details 
Original Abstract of the Article :
BACKGROUND: Hyperkalemia is associated with many chronic diseases and renin-angiotensin-aldosterone system inhibitor therapy. Sodium zirconium cyclosilicate (SZC), an oral, highly selective cation-exchanger, is approved for the treatment of hyperkalemia. METHODS: This phase 3, multicenter, open-lab...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880936/

データ提供:米国国立医学図書館(NLM)

Sodium Zirconium Cyclosilicate: A Long-Term Safety Study for Hyperkalemia

This study delves into the realm of nephrology, exploring the long-term safety of sodium zirconium cyclosilicate (SZC), a medication used to treat hyperkalemia, a condition where potassium levels in the blood are dangerously high. The researchers, like intrepid explorers venturing into the unknown, conducted a phase 3, multicenter, open-label, single-arm, flexible-dose study. This research is like a careful journey through the desert, assessing the effects of SZC over a year. The researchers found that SZC was well-tolerated by patients with hyperkalemia, indicating that it is a safe and effective long-term treatment option. It's as if SZC acts as a stabilizing force in the body, bringing order to the potassium levels and ensuring a comfortable journey for the patient.

SZC: A Stable Treatment for Hyperkalemia

The study showed that SZC effectively controls potassium levels in patients with hyperkalemia. The results suggest that SZC is a safe and well-tolerated treatment option for individuals struggling with this condition, offering a stable and effective approach to managing their potassium levels.

A Promising Future for Hyperkalemia Treatment

This study highlights the potential of SZC as a safe and effective treatment for hyperkalemia. It's like finding a hidden spring in the desert, offering a steady source of relief and hope for patients seeking to manage their potassium levels.

Dr.Camel's Conclusion

SZC shines as a beacon of hope in the desert of hyperkalemia. This study demonstrates that SZC offers a safe and effective long-term treatment option, bringing stability and relief to patients struggling with this challenging condition.

Date :
  1. Date Completed 2021-11-01
  2. Date Revised 2023-11-10
Further Info :

Pubmed ID

33098526

DOI: Digital Object Identifier

PMC7880936

Related Literature

SNS
PICO Info
in preparation
Languages

English

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