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Transient Improvement after Switch to Low Doses of RimabotulinumtoxinB in Patients Resistant to AbobotulinumtoxinA.

Author: HefterHarald, MollMarek, SamadzadehSara

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Observational StudyResearch that observes and collects data on participants' behavior and outcomes in their natural state, without intervention.

Overview

This study compared the clinical effect of rimabotulinumtoxinB to abobotulinumtoxinA in patients resistant to BoNT/A.
Paper Details　
Original Abstract of the Article :
Botulinum toxin type B (BoNT/B) has been recommended as an alternative for patients who have become resistant to botulinum toxin type A (BoNT/A). This study aimed to compare the clinical effect, within a patient, of four injections with low doses of rimabotulinumtoxinB with the effect of the precedi...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693617/

データ提供：米国国立医学図書館（NLM）

Botulinum Toxin: Navigating the Desert of Resistance

Botulinum toxin, like a potent desert flower, can provide a temporary reprieve from muscle spasms. However, for some patients, the effects of botulinum toxin type A (BoNT/A) eventually fade, leaving them feeling like they've lost their way in a desert of resistance. The researchers in this study explored the potential of botulinum toxin type B (BoNT/B) as a new path to relief.

Switching to Lower Doses of BoNT/B

The study found that switching to lower doses of rimabotulinumtoxinB (BoNT/B) can bring about a temporary improvement for patients who have become resistant to BoNT/A. This finding is like discovering a hidden spring of water in the desert, offering a renewed source of relief.

A Potential Solution for BoNT/A Resistance

This research offers a potential solution for patients who have become resistant to BoNT/A, but it's important to note that this study was limited by its small sample size. Further research is needed to fully understand the long-term efficacy and safety of BoNT/B as an alternative treatment.

Dr.Camel's Conclusion

This study provides a potential roadmap for navigating the desert of BoNT/A resistance. While the findings are encouraging, more research is needed to confirm the efficacy and safety of BoNT/B for the long term.

Date :
  1. Date Completed 2021-07-08
  2. Date Revised 2021-07-08
Further Info :

Pubmed ID

33121133

DOI: Digital Object Identifier

PMC7693617

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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