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Molecular identification, biofilm formation and antifungal susceptibility of Rhodotorula spp.
Author: GharaghaniMaral, TaghipourSimin, Zarei MahmoudabadiAli
Original Abstract of the Article :
Luliconazole is an imidazole antifungal agent used in topical form for the treatment of onychomycosis and dermatophytosis. In vitro activity of luliconazole against dermatophytes, Candida, black fungi, Fusarium and Aspergillus species have been investigated. Rhodotorula spp. are environmental yeasts...See full text at original site
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引用元:
https://doi.org/10.1007/s11033-020-05942-1
データ提供:米国国立医学図書館(NLM)
Luliconazole and Rhodotorula: Exploring Antifungal Resistance
Fungal infections are becoming increasingly prevalent, posing a significant challenge to healthcare systems worldwide. This study investigates the antifungal susceptibility of Rhodotorula spp., a group of environmental yeasts that have emerged as opportunistic pathogens, particularly in immunocompromised patients. The study focuses on the effectiveness of luliconazole, a topical antifungal agent, against these yeast isolates, comparing its activity to other commonly used antifungals.
Luliconazole's Limitations Against Rhodotorula: A Challenge for Antifungal Treatment
The study reveals that luliconazole exhibits limited efficacy against Rhodotorula spp., with high minimum inhibitory concentrations (MIC) values. Furthermore, the study highlights the widespread resistance of Rhodotorula spp. to other antifungal drugs, particularly caspofungin, fluconazole, and voriconazole. This finding underscores the importance of exploring alternative antifungal agents and treatment strategies for combating Rhodotorula infections.
Navigating the Complex World of Antifungal Resistance: A Call for Innovation
This study serves as a stark reminder of the growing challenge of antifungal resistance. It highlights the need for continued research and development of new antifungal agents and treatment approaches to effectively combat these increasingly resistant fungal infections. This research is like finding a hidden oasis in the vast desert of antifungal resistance, offering a glimpse of the challenges and opportunities that lie ahead.
Dr.Camel's Conclusion
This study is a journey through the desert of antifungal resistance, revealing the challenges posed by Rhodotorula spp. and the limitations of current antifungal agents. It underscores the need for innovative approaches to combat these infections, emphasizing the urgency of developing new drugs and strategies to combat this growing threat to human health.
Date :
- Date Completed 2021-05-24
- Date Revised 2021-05-24
Further Info :
Related Literature
English
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