Role of salvage lymph node dissection in patients previously treated for prostate cancer: systematic review.

Author: Alcantara-QuispeCinthia, FantinJoão Paulo Pretti, FariaEliney Ferreira, FurstMaria Claudia Bicudo, MachadoRoberto Dias, MagnaboscoWesley Justino, MullerRoberto Lodeiro, SantosAlexandre Cesar, Tobias-MachadoMarcos

Paper Details 
Original Abstract of the Article :
Prostate cancer is the most common invasive cancer in men. Radical prostatectomy (RP) is a definitive treatment option, but biochemical recurrence can reach 40%. Salvage lymphadenectomy is a relatively recent approach to oligometasis and has been rapidly diffused primarily due to improvement in imag...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993961/

データ提供:米国国立医学図書館(NLM)

Salvage Lymph Node Dissection: A Second Chance for Prostate Cancer Patients?

Prostate cancer, a common malignancy among men, can sometimes recur even after initial treatment with radical prostatectomy. This research explores the role of salvage lymph node dissection, a relatively new approach to treating oligometastases, as a potential solution for biochemical recurrence. The authors conducted a systematic review of the literature, analyzing data from 27 studies involving 1,714 patients who underwent salvage lymphadenectomy after previous treatment for localized prostate cancer. They found that biochemical response rates varied significantly across studies, ranging from 0% to 80%. The study also examined the impact on biochemical recurrence-free survival, with rates varying from 0% to 56.1%. While the authors acknowledge the lack of high-level evidence to draw firm conclusions, they suggest that salvage lymphadenectomy may offer promising oncological results and potentially delay the need for systemic therapy. Further research is needed to determine the long-term impact on overall survival, quality of life, and the most appropriate strategies for case selection.

A Second Chance: Exploring Salvage Lymph Node Dissection for Prostate Cancer

This research offers a glimpse into the potential of salvage lymph node dissection as a treatment option for prostate cancer patients experiencing biochemical recurrence. The study reveals promising results in terms of biochemical response and delaying the need for systemic therapy. However, the authors emphasize the need for further research to fully understand its impact on long-term outcomes. This research represents a significant step in the ongoing quest for effective treatments for prostate cancer.

Navigating Prostate Cancer Treatment: A Multi-faceted Approach

The research highlights the complexity of prostate cancer treatment and the importance of individualizing treatment plans based on the patient's specific circumstances. While salvage lymph node dissection shows promise, further research is needed to optimize its use and ensure the best possible outcomes for patients. It's a reminder that advancements in cancer care are an ongoing process, with researchers continuously seeking new and improved therapies. This research contributes to our understanding of prostate cancer and its potential treatments, paving the way for a brighter future for patients.

Dr. Camel's Conclusion

This research provides a valuable overview of the potential role of salvage lymph node dissection in managing prostate cancer recurrence. While the findings are promising, the authors acknowledge the need for more research to fully understand its long-term impact. This highlights the ever-evolving nature of cancer research and the importance of continually seeking new and improved therapies to optimize patient outcomes. The study encourages collaboration and further investigation to unlock the full potential of salvage lymphadenectomy in the fight against prostate cancer.

Date :
  1. Date Completed 2021-04-23
  2. Date Revised 2021-04-23
Further Info :

Pubmed ID

33146973

DOI: Digital Object Identifier

PMC7993961

Related Literature

SNS
PICO Info
in preparation
Languages

English

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