Efficacy of nifedipine versus hydralazine in the management of severe hypertension in pregnancy: A randomised controlled trial.

Author: AdebayoJoshua Adeniyi, AdieleNnabugwu Alfred, EsikeChidi Ochu, LawaniLucky Osaheni, NwaforJohnbosco Ifunanya, OlaleyeAyodele Adegbite

Paper Details 
Original Abstract of the Article :
BACKGROUND: Despite the availability of effective antihypertensive drugs, the quality of evidence regarding the best antihypertensive agent for the treatment of hypertensive emergencies in pregnancy is still poor. AIM: The aim of this study was to compare the efficacy and side effects of oral nifed...See full text at original site
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引用元:
https://doi.org/10.4103/npmj.npmj_275_20

データ提供:米国国立医学図書館(NLM)

Managing Severe Hypertension in Pregnancy: A Balancing Act

Hypertension during pregnancy can be a serious concern, requiring careful management to ensure the health of both mother and baby. This randomized controlled trial, published in [Journal name], aimed to compare the efficacy and side effects of oral nifedipine and intravenous hydralazine in controlling severe hypertension in pregnancy. The study enrolled 78 pregnant women with severe hypertension, randomly assigning them to receive either nifedipine or hydralazine.

Nifedipine: A Potential Advantage

The study found that the average number of doses needed to achieve targeted blood pressure was lower in the nifedipine group. However, both nifedipine and hydralazine demonstrated comparable efficacy in controlling blood pressure, and there were no significant differences in adverse maternal or perinatal outcomes. Further research is needed to understand the long-term effects of these drugs in pregnancy.

Navigating the Shifting Sands of Pregnancy Care

Managing severe hypertension in pregnancy is a delicate dance, requiring careful consideration of both maternal and fetal health. This study, like a guide through a desert landscape, provides valuable insights into the efficacy of two different antihypertensive medications. While nifedipine may offer a potential advantage in terms of dosage, more research is needed to understand the best course of action for pregnant women with severe hypertension.

Dr.Camel's Conclusion

Pregnancy is a journey through a dynamic landscape, and managing hypertension during this time is akin to navigating a sandstorm. This study offers a clearer view of the options available, highlighting the potential benefits of nifedipine, but also reminding us that further exploration is essential to ensure the safest and most effective path for both mother and baby.
Date :
  1. Date Completed 2021-01-14
  2. Date Revised 2022-04-18
Further Info :

Pubmed ID

33154284

DOI: Digital Object Identifier

10.4103/npmj.npmj_275_20

SNS
PICO Info
in preparation
Languages

English

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