Oral Alitretinoin for Patients with Refractory Prurigo.

Author: ChungBo Young, JungMin Je, KangSeok Young, KimHye One, KimJin Cheol, KwakIn-Suk, ParkChun Wook, UmJi Young

Paper Details 
Original Abstract of the Article :
<i>Background</i>: prurigo is a chronic skin disorder associated with a history of chronic pruritus. The pathogenesis of prurigo is largely unknown and the treatment of prurigo is unsatisfactory and challenging. Conventional systemic treatments may be beneficial; however, their possible side effect...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695266/

データ提供:米国国立医学図書館(NLM)

Oral Alitretinoin: A Potential Oasis in the Desert of Prurigo

Dermatology, a field as vast as the Sahara, constantly faces challenges in treating chronic skin conditions like prurigo. This research delves into the potential benefits of oral alitretinoin as a therapeutic oasis for patients struggling with refractory prurigo nodularis. The study employed a retrospective approach, analyzing medical records of 10 patients who had exhausted conventional therapies like antihistamines, cyclosporine, and phototherapy. The findings indicate that oral alitretinoin brought relief from pruritus and improved skin lesions within 2 to 3 months, suggesting its potential as a well-tolerated treatment option.

A Beacon of Hope in the Desert of Refractory Prurigo

The study's results offer a glimmer of hope for patients who have traversed the desert of conventional treatment options, finding little solace. The fact that alitretinoin brought relief to all patients, regardless of their individual circumstances, speaks volumes about its potential efficacy.

A Sip of Water in the Desert: Considering Alitretinoin

While the study suggests promise, further research is vital to quench our thirst for a definitive answer. Long-term studies are crucial to confirm the enduring efficacy and safety of alitretinoin for prurigo management. Until then, consider this research as a helpful guide in the desert, offering a potential path towards improved quality of life.

Dr. Camel's Conclusion

This research, like a refreshing spring in the desert, provides a beacon of hope for patients struggling with intractable prurigo. It's important to remember that more research is needed before we can confidently declare alitretinoin as a definitive oasis in the desert of this chronic skin condition. However, the findings offer valuable insights into a potential treatment approach, highlighting the importance of continued exploration in the vast landscape of dermatological research.

Date :
  1. Date Completed 2021-05-14
  2. Date Revised 2021-05-14
Further Info :

Pubmed ID

33182351

DOI: Digital Object Identifier

PMC7695266

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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