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Nabumetone in the treatment of active adult rheumatoid arthritis.

Author: BrobynR D

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.

Overview

Nabumetone (1,000 mg once daily) was found to be as effective as naproxen (250 mg twice daily) in treating 84 patients with rheumatoid arthritis. Both drugs were well tolerated.
Paper Details　
Original Abstract of the Article :
One hundred patients were entered in a six-month, double-blind comparison of 1,000 mg nabumetone once daily and 250 mg naproxen twice daily. Forty-two patients in each arm of the study were evaluable for efficacy; all were evaluable for safety. There was a low incidence of adverse experiences during...See full text at original site
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引用元：
https://doi.org/10.1016/0002-9343(87)90594-8

データ提供：米国国立医学図書館（NLM）

Nabumetone: An Effective and Safe Treatment for Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic autoimmune disease that can cause significant pain, inflammation, and joint damage. This study investigates the effectiveness and safety of nabumetone, a nonsteroidal anti-inflammatory drug (NSAID), in treating active adult RA. The researchers conducted a six-month, double-blind, randomized controlled trial comparing nabumetone to naproxen, another NSAID commonly used for RA. The study's findings demonstrate that nabumetone is at least as effective as naproxen in managing RA symptoms and has an acceptable safety profile for long-term use.

Nabumetone: A Viable Option for RA Treatment

The study found that nabumetone was as effective as naproxen in reducing RA symptoms, with both drugs showing comparable improvement in pain, stiffness, and function. The researchers also noted that nabumetone had a low incidence of adverse experiences, with no patients withdrawing from the study due to side effects. The findings suggest that nabumetone is a safe and effective treatment option for RA, offering a viable alternative to other NSAIDs. The study's findings provide valuable insights into the therapeutic potential of nabumetone for managing RA.

Navigating the Desert of Rheumatoid Arthritis

RA is a chronic condition that can significantly impact a person's quality of life. This study provides hope for individuals struggling with RA, highlighting the effectiveness and safety of nabumetone as a treatment option. The study's findings underscore the importance of ongoing research to develop new and improved therapies for RA, helping individuals manage their symptoms and live fulfilling lives.

Dr. Camel's Conclusion

This research is like a refreshing oasis in the desert of rheumatoid arthritis management. It provides valuable insights into the effectiveness and safety of nabumetone, offering a viable treatment option for individuals struggling with this chronic condition. The findings encourage us to continue exploring new avenues for managing RA and improving the lives of those affected by this debilitating disease.

Date :
  1. Date Completed 1987-12-23
  2. Date Revised 2019-06-26
Further Info :

Pubmed ID

3318429

DOI: Digital Object Identifier

10.1016/0002-9343(87)90594-8

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・Side Effects of nabumetone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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