Controlled evaluation of nabumetone in the treatment of active adult rheumatoid arthritis. Nabumetone versus naproxen double-blind parallel study.

Author: BockowB I, BoxP, BrodskyA L, EspinozaL R, FleischmannR M, FogariR A, GermainB F, LipaniJ A, MullenB J, VaseyF B

Paper Details 
Original Abstract of the Article :
Nabumetone is a new nonsteroidal anti-inflammatory agent. Therapy with nabumetone 1,000 mg given at bedtime was compared with naproxen 250 mg given twice daily in a prospective double-blind study of patients with rheumatoid arthritis. Both drugs were found to be efficacious in a comparable fashion. ...See full text at original site
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引用元:
https://doi.org/10.1016/0002-9343(87)90595-x

データ提供:米国国立医学図書館(NLM)

Nabumetone: A New Contender in Rheumatoid Arthritis Treatment

The field of rheumatology is constantly seeking to improve treatment options for chronic inflammatory conditions like rheumatoid arthritis (RA). This research investigates the efficacy and safety of nabumetone, a new nonsteroidal anti-inflammatory drug (NSAID), in the treatment of active adult RA. The authors conducted a prospective, double-blind, parallel study comparing nabumetone to naproxen, a well-established NSAID. This study's findings are particularly relevant given the need for effective and well-tolerated NSAIDs for the management of RA, a debilitating condition affecting millions worldwide.

Nabumetone: A Promising New NSAID for RA

This double-blind study provides valuable evidence for the efficacy and tolerability of nabumetone in the treatment of active adult RA. The findings demonstrate that nabumetone is comparable to naproxen in terms of effectiveness, with similar patient withdrawal rates and gastrointestinal side effect profiles. This study suggests that nabumetone could be a valuable addition to the therapeutic options for RA, offering patients a potential alternative to existing NSAIDs.

Managing RA: A Multifaceted Approach

The development of new and effective NSAIDs like nabumetone is crucial for managing RA, a chronic condition that can significantly impact quality of life. This research underscores the importance of ongoing research to identify and evaluate novel therapeutic agents for the treatment of RA, ensuring that patients have access to the best possible care. It also emphasizes the need for a multidisciplinary approach to RA management, involving medication, physical therapy, and lifestyle modifications to optimize outcomes.

Dr.Camel's Conclusion

Just as a desert oasis provides relief to weary travelers, new treatments for RA like nabumetone offer hope for individuals struggling with this debilitating condition. This research, like a well-charted path through the desert, guides us towards a better understanding of the efficacy and safety of nabumetone. By embracing a comprehensive and patient-centered approach, we can provide effective care for those living with RA, empowering them to live fulfilling lives despite the challenges they face.

Date :
  1. Date Completed 1987-12-23
  2. Date Revised 2019-06-26
Further Info :

Pubmed ID

3318430

DOI: Digital Object Identifier

10.1016/0002-9343(87)90595-x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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