Effect of combination treatment based on interferon and nucleos(t)ide analogues on functional cure of chronic hepatitis B: a systematic review and meta-analysis.

Author: ChengYongqian, HeQing, LiuJiaye, WangFu-Sheng, WangTingyan, ZhangWei

Paper Details 
Original Abstract of the Article :
Priority of antiviral treatment for patients with chronic hepatitis B (CHB) is to increase the probability of functional cure. We aimed to synthesize evidence regarding the efficacy of different combination strategies of antiviral treatment based on interferon (IFN) and nucleos(t)ide analogues (NAs)...See full text at original site
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引用元:
https://doi.org/10.1007/s12072-020-10099-x

データ提供:米国国立医学図書館(NLM)

Chronic Hepatitis B: A Quest for Functional Cure

In the vast desert of medical research, the quest for a functional cure for chronic hepatitis B (CHB) continues. This study, like a thirsty camel seeking an oasis, dives deep into the efficacy of different combination strategies of antiviral treatment based on interferon (IFN) and nucleos(t)ide analogues (NAs) in adults with CHB. The authors used a systematic review and meta-analysis, akin to a meticulously mapped route across the dunes, to synthesize evidence regarding the efficacy of these treatment strategies. They discovered some promising results, particularly regarding the increase in the probability of functional cure. Their findings shed light on the potential of these combinations to bring hope to individuals battling CHB.

Unlocking the Potential of Combination Therapies

The study indicates that certain combination strategies involving IFN and NAs, such as a carefully crafted blend of ingredients in a desert spice mix, hold great promise for improving functional cure outcomes in adults with CHB. This is a significant step forward in the fight against this persistent liver infection.

Navigating the Path to Improved Liver Health

With this promising research, we are given a glimpse of a future where the threat of chronic hepatitis B may be more manageable. The findings encourage further exploration of combination therapies tailored to individual patient needs, paving the way for a healthier tomorrow.

Dr. Camel's Conclusion

This study provides a valuable roadmap for researchers and clinicians, guiding them through the complexities of chronic hepatitis B treatment. Like a caravan venturing into the unknown, we must continue to pursue innovative strategies, leaving no stone unturned in our quest for a functional cure.
Date :
  1. Date Completed 2021-10-29
  2. Date Revised 2021-10-29
Further Info :

Pubmed ID

33185803

DOI: Digital Object Identifier

10.1007/s12072-020-10099-x

SNS
PICO Info
in preparation
Languages

English

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