Ex vivo machine perfusion: current applications and future directions in liver transplantation.

Author: GassnerJoseph M G V, MichelottoJulian, MoosburnerSimon, MuthVanessa, PatelMadhukar S, PratschkeJohann, RaschzokNathanael, SauerIgor M, SelznerMarkus

Paper Details 
Original Abstract of the Article :
BACKGROUND: Liver transplantation is the only curative treatment option for end-stage liver disease; however, its use remains limited due to a shortage of suitable organs. In recent years, ex vivo liver machine perfusion has been introduced to liver transplantation, as a means to expand the donor or...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870621/

データ提供:米国国立医学図書館(NLM)

Ex Vivo Liver Machine Perfusion: A Promising Solution for Liver Transplantation

Liver transplantation, the only curative treatment for end-stage liver disease, faces a constant challenge – a shortage of suitable donor organs. Researchers, like explorers seeking a new route through a vast desert, are continuously exploring innovative approaches to expand the donor organ pool.

Ex vivo liver machine perfusion, a revolutionary technology, offers a promising solution to this critical challenge. This technique involves maintaining donor livers outside the body using a specialized machine, allowing for organ assessment, reconditioning, and potential recovery of previously unsuitable organs. This innovation, like a camel's ability to access water sources hidden deep within the desert, expands our ability to utilize donor organs and save lives.

Ex Vivo Liver Machine Perfusion: A Game-Changer for Organ Transplantation

This review highlights the exciting potential of ex vivo liver machine perfusion in revolutionizing liver transplantation. It offers a promising strategy for expanding the donor pool and improving the availability of life-saving organs. This development, like a desert traveler discovering a new oasis, provides a beacon of hope for individuals awaiting life-saving liver transplantation.

The Future of Liver Transplantation: A Collaborative Effort

The future of liver transplantation hinges on a collaborative effort between researchers, clinicians, and organ procurement organizations. Continued research, refinement of ex vivo machine perfusion technology, and increased awareness of its potential will be crucial in expanding access to this life-saving procedure. Just as a camel's ability to navigate the desert depends on a combination of physical adaptations and environmental understanding, the success of liver transplantation relies on a collaborative and innovative approach.

Dr.Camel's Conclusion

Ex vivo liver machine perfusion is a game-changer in the field of liver transplantation, offering a promising solution to the critical shortage of donor organs. Like a camel's ability to adapt to the harsh desert environment, this technology expands our ability to utilize donor organs and provide life-saving treatments for those in need.

Date :
  1. Date Completed 2021-09-24
  2. Date Revised 2023-11-10
Further Info :

Pubmed ID

33216216

DOI: Digital Object Identifier

PMC7870621

Related Literature

SNS
PICO Info
in preparation
Languages

English

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