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Effects of Histamine Receptor Antagonist Cetirizine on Orthodontic Tooth Movement.

Author: DeschnerJames, GattnerJohanna, KirschneckChristian, ProffPeter, SchröderAgnes, SperlGregor, WolfMichael

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study evaluated the effect of cetirizine, a histamine receptor antagonist, on orthodontic tooth movement in rats. The results showed that cetirizine, at clinically relevant dosages, did not significantly affect orthodontic tooth movement, indicating that it can be used safely during orthodontic treatment to prevent allergic reactions.
Paper Details　
Original Abstract of the Article :
Many patients regularly take histamine receptor antagonists, such as cetirizine, to prevent allergic reactions, but these antiallergic drugs may have inadvertent effects on orthodontic treatment. In previous studies, histamine has been shown to modulate the sterile inflammatory reaction underlying o...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762581/

データ提供：米国国立医学図書館（NLM）

Cetirizine and Orthodontic Tooth Movement: A Peaceful Coexistence?

Orthodontic treatment involves moving teeth to improve alignment and bite. Many individuals take histamine receptor antagonists like cetirizine to manage allergies. This study examines the potential impact of cetirizine on orthodontic tooth movement, addressing a vital question: does taking cetirizine interfere with orthodontic treatment?

No Interference with Orthodontic Progress

The study found that cetirizine, at both clinically relevant and higher doses, did not significantly affect tooth movement, bone growth, or other aspects of orthodontic treatment in rats. This suggests that cetirizine can be used safely during orthodontic treatment without hindering the desired results.

A Reassuring Outcome for Patients

This research provides reassurance to patients undergoing orthodontic treatment who also require cetirizine for allergies. They can continue their allergy medication without fear of affecting their orthodontic progress. This is excellent news for those who want to achieve the desired results without compromising their health.

Dr.Camel's Conclusion

This study provides encouraging news for individuals undergoing orthodontic treatment who also need cetirizine for allergy management. The results show that cetirizine does not interfere with tooth movement, allowing patients to achieve their desired orthodontic outcomes while managing their allergies effectively.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-12-29
Further Info :

Pubmed ID

33302395

DOI: Digital Object Identifier

PMC7762581

Related Literature

Article Analysis
・Side Effects of cetirizine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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