Paper Details 
Original Abstract of the Article :
We present here a case of ALK-positive lung adenocarcinoma that has been started on Alectinib. Treatment has been initiated at the recommended initial dose, but it subsequently required a dose adjustment following adverse drug events. Alectinib is a second-generation, CNS-active, tyrosine kinase inh...See full text at original site
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引用元:
https://doi.org/10.1016/j.ctarc.2021.100319

データ提供:米国国立医学図書館(NLM)

Revisiting the Starting Dose of Alectinib in ALK-Positive Non-Small Cell Lung Cancer

This case report explores the use of alectinib, a second-generation tyrosine kinase inhibitor, for the treatment of ALK-positive non-small cell lung cancer (NSCLC). The authors present a case of an ALK-positive lung adenocarcinoma patient who experienced adverse drug events after starting alectinib at the recommended initial dose, requiring a dose adjustment. The authors highlight the potential need to consider a lower starting dose of alectinib, particularly in patients with lower body weight. The case report emphasizes the importance of individualized treatment approaches and careful monitoring for adverse events in patients receiving alectinib therapy.

Navigating the Desert of Lung Cancer Treatment

This case report is like a guidepost in the vast desert of lung cancer treatment, highlighting the importance of individualizing treatment plans and carefully considering factors such as patient weight. The findings suggest the potential need for more nuanced approaches to alectinib dosing to optimize treatment outcomes and minimize adverse events.

Finding a Path to Success in the Desert of Lung Cancer

The fight against lung cancer is a challenging journey, but advancements in targeted therapies like alectinib offer hope for patients. This case report emphasizes the importance of ongoing research, individualized care, and meticulous monitoring to optimize treatment outcomes and improve patient quality of life. Just as a camel navigates the desert with resilience, we must be persistent in our pursuit of better treatments for lung cancer.

Dr.Camel's Conclusion

This case report highlights the importance of individualized treatment approaches and careful monitoring for adverse events in patients receiving alectinib therapy. The findings suggest the potential need for more nuanced approaches to alectinib dosing, particularly in patients with lower body weight. Remember, just as a camel adapts to the harsh desert environment, we must be flexible and adaptable in our approach to lung cancer treatment.

Date :
  1. Date Completed 2021-12-31
  2. Date Revised 2021-12-31
Further Info :

Pubmed ID

33515938

DOI: Digital Object Identifier

10.1016/j.ctarc.2021.100319

Related Literature

SNS
PICO Info
in preparation
Languages

English

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