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A Systematic Literature Review and Indirect Treatment Comparison of Efficacy of Repository Corticotropin Injection versus Synthetic Adrenocorticotropic Hormone for Infantile Spasms.
Author: ChopraIshveen, DevineBeth, DuchownyMichael S, NiewoehnerJohn, WanGeorge J
Original Abstract of the Article :
<b>Background:</b> Infantile spasms is a rare disease characterized by distinct seizures and hypsarrhythmia. Adrenocorticotropic hormone (ACTH) is available as a natural product (repository corticotropin injection, [RCI]; Acthar® Gel) and as synthetic analogs. RCI is a naturally-sourced comple...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839629/
データ提供:米国国立医学図書館(NLM)
Comparing the Efficacy of ACTH Treatments for Infantile Spasms
The field of [neurology] constantly seeks to improve treatment options for [infantile spasms], a rare condition characterized by distinct seizures and hypsarrhythmia. This research compares the efficacy of two different types of [ACTH] treatments: [repository corticotropin injection] and [synthetic ACTH analogs]. The study utilizes a [systematic review and indirect treatment comparison] approach, analyzing data from multiple clinical trials. The findings provide valuable insights into the relative efficacy of these treatment options, informing future research and clinical decision-making.
Repository Corticotropin Injection Shows Promise
This research suggests that [repository corticotropin injection] may be more effective than [synthetic ACTH analogs] in treating [infantile spasms]. The study found that the odds of achieving efficacy outcomes were significantly higher with [repository corticotropin injection] compared to [tetracosactide] and [corticotropin carboxymethyl-cellulose]. This implies that [repository corticotropin injection] may be a better option for treating [infantile spasms], but more research is needed to confirm these findings.
The Importance of Personalized Treatment
These findings underscore the importance of individualized treatment approaches for [infantile spasms], considering the various [ACTH] treatment options available. The research emphasizes the importance of carefully evaluating patient characteristics and the specific needs of each individual to determine the most appropriate treatment option.
Dr.Camel's Conclusion
This research explores the comparative efficacy of [repository corticotropin injection] and [synthetic ACTH analogs] in treating [infantile spasms]. The study provides valuable information that can help inform clinical decision-making, particularly regarding the choice of [ACTH] treatment. The authors call for further research to confirm these findings and to explore the long-term effects of these different treatments.
Date :
- Date Completed n.d.
- Date Revised 2023-10-10
Further Info :
Related Literature
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