Causality and avoidability of adverse drug reactions of antibiotics in hospitalized children: a cohort study.

Author: Aires-MorenoGiulyane Targino, Araújo-NetoFernando de Castro, LimaElisângela da Costa, RamosSheila Feitosa, de AraújoDyego Carlos Souza Anacleto, de LyraDivaldo Pereira

Paper Details 
Original Abstract of the Article :
BACKGROUND: Adverse drug reactions are a problem in healthcare systems worldwide. Children are more susceptible than adults, especially when exposed to specific drug classes, such as antibiotics. OBJECTIVE: To assess the incidence, causality, severity, and avoidability of antibiotic-associated adve...See full text at original site
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引用元:
https://doi.org/10.1007/s11096-021-01249-8

データ提供:米国国立医学図書館(NLM)

Antibiotic-Associated Adverse Drug Reactions in Hospitalized Children

This study investigates the incidence, causality, severity, and avoidability of antibiotic-associated adverse drug reactions in hospitalized pediatric patients. The researchers conducted a prospective cohort study in a pediatric ward in Brazil, using established assessment tools to evaluate adverse drug reactions.

Understanding Drug Reactions in Children

The study found that antibiotic-associated adverse drug reactions were common in hospitalized children, with a significant proportion being classified as moderate severity, probable causality, and potentially avoidable. The most frequently implicated antibiotics were ceftriaxone, azithromycin, and crystalline penicillin.

Preventing Adverse Drug Reactions in Children

This study highlights the crucial need for careful antibiotic prescribing practices in children. The authors emphasize the importance of implementing preventive measures and monitoring the use of antibiotics to ensure patient safety. As a camel who knows the delicate balance of ecosystems, I am acutely aware of the importance of minimizing unnecessary interventions and maximizing beneficial outcomes.

Dr.Camel's Conclusion

This research underscores the importance of meticulous attention to detail, especially when treating vulnerable populations like children. It provides valuable insights for pediatricians and pharmacists who must navigate the complex landscape of drug interactions and potential adverse effects. As we continue to explore the vast desert of medical knowledge, we must remain vigilant and dedicated to protecting the most vulnerable members of our community.
Date :
  1. Date Completed 2021-10-15
  2. Date Revised 2021-10-15
Further Info :

Pubmed ID

33656658

DOI: Digital Object Identifier

10.1007/s11096-021-01249-8

Related Literature

SNS
PICO Info
in preparation
Languages

English

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