Factors associated with premature medication discontinuation among responders to an MAOI or a tricyclic antidepressant.

Author: AgostiV, MarkowitzJ, McGrathP J, QuitkinF M, RabkinJ G, StewartJ W

Paper Details 
Original Abstract of the Article :
The charts of 80 outpatients who responded to antidepressants were reviewed to determine if there was a higher rate of premature medication discontinuation with phenelzine than with imipramine. The phenelzine responders had a significantly (p less than .01) higher rate of drug discontinuation, mainl...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/3366755

データ提供:米国国立医学図書館(NLM)

Medication Discontinuation in Patients Responding to Antidepressants

This study, conducted in the field of psychiatry, explores the issue of premature medication discontinuation in patients responding to antidepressants. It's like trying to navigate a desert while carrying a heavy load, sometimes the journey becomes too difficult to continue. The study compares the rates of discontinuation for phenelzine (an MAOI) and imipramine (a tricyclic antidepressant) in 80 outpatients who responded to antidepressants. The researchers found that phenelzine responders had a significantly higher rate of drug discontinuation, primarily due to side effects.

Navigating the Desert of Side Effects

The study highlights the challenges of managing side effects in patients taking antidepressants. It's like encountering sandstorms on a desert trek, where you must find ways to shelter and adapt. The researchers suggest that the high discontinuation rate associated with phenelzine could be related to its side effect profile.

Navigating the Desert of Mental Health

Mental health is a delicate landscape, much like a desert, where finding the right path is crucial. It's important to work closely with your doctor to find an antidepressant that effectively manages your symptoms while minimizing side effects.

Dr. Camel's Conclusion

This study emphasizes the need for careful monitoring and individualized treatment approaches when prescribing antidepressants, as side effects can significantly impact medication adherence. Further research is needed to better understand the reasons behind medication discontinuation and to develop strategies to improve patient outcomes.

Date :
  1. Date Completed 1988-06-21
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

3366755

DOI: Digital Object Identifier

3366755

Related Literature

SNS
PICO Info
in preparation
Languages

English

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