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Safety and immunogenicity of inactivated hepatitis-A vaccine developed by Human Biologicals Institute in two age groups of healthy subjects: A phase I open label study.
Author: BarsodeSupriya, DiwanArundhati, LingalaRajendra, PalkarSonali, RajashakarB C, SahooDevi Prasad, SandhyaG, SatishM, SusarlaSai Krishna, SvPardha Saradhi
Original Abstract of the Article :
Hepatitis-A is an acute viral infection of the liver. Hepatitis-A virus has worldwide spread and is endemic in India. Though the disease is self-limiting in most cases, outbreaks are reported frequently from both developing and developed countries of the world. Severity and fatality occur more among...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.vaccine.2021.03.012
データ提供:米国国立医学図書館(NLM)
Inactivated Hepatitis-A Vaccine: A Shield Against a Global Threat
Hepatitis-A is a serious public health concern, with widespread outbreaks reported worldwide. This study, like a camel navigating a desert landscape, explores the safety and immunogenicity of an inactivated hepatitis-A vaccine developed by the Human Biologicals Institute. The researchers, using a [phase I, single arm, open label, multicenter trial], assessed the vaccine's safety and efficacy in two different age groups. Their findings, like an oasis providing much-needed relief, demonstrated that the vaccine was well-tolerated and elicited a robust immune response in both age groups, highlighting its potential as a valuable tool for preventing hepatitis-A infection.
A Vital Tool for Prevention: The Role of Hepatitis-A Vaccination
This study's findings, like a protective shield in the desert, emphasize the importance of vaccination in preventing hepatitis-A infection. The vaccine's safety and efficacy offer a powerful weapon in combating this global health threat.
Protecting Communities: The Benefits of Vaccination
Vaccination is a crucial tool for protecting individuals and communities from infectious diseases. By increasing vaccination rates, we can create a barrier against the spread of diseases like hepatitis-A, safeguarding the health and well-being of populations.
Dr.Camel's Conclusion
This study, like a camel carrying precious cargo through the desert, highlights the importance of vaccination in safeguarding public health. The findings demonstrate the safety and immunogenicity of an inactivated hepatitis-A vaccine, offering a vital tool for preventing this potentially serious infection.
Date :
- Date Completed 2021-05-24
- Date Revised 2022-05-31
Further Info :
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English
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